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- W3143080003 abstract "From time immemorial, mushrooms have been valued by humankind as a culinary wonder and folk medi- cine in Oriental practice. The last decade has witnessed the overwhelming interest of western research fraternity in pharmaceutical potential of mushrooms. The chief medici- nal uses of mushrooms discovered so far are as anti-oxidant, anti-diabetic, hypocholesterolemic, anti-tumor, anti-cancer, immunomodulatory, anti-allergic, nephroprotective, and anti-microbial agents. The mushrooms credited with success against cancer belong to the genus Phellinus, Pleurotus, Agaricus, Ganoderma, Clitocybe, Antrodia, Trametes, Cordyceps, Xerocomus, Calvatia, Schizophyllum, Flammu- lina, Suillus, Inonotus, Inocybe, Funlia, Lactarius, Alba- trellus, Russula, and Fomes. The anti-cancer compounds play crucial role as reactive oxygen species inducer, mitotic kinase inhibitor, anti-mitotic, angiogenesis inhibitor, topoi- somerase inhibitor, leading to apoptosis, and eventually checking cancer proliferation. The present review updates the recent findings on the pharmacologically active com- pounds, their anti-tumor potential, and underlying mecha- nism of biological action in order to raise awareness for further investigations to develop cancer therapeutics from mushrooms. The mounting evidences from various research groups across the globe, regarding anti-tumor application of mushroom extracts unarguably make it a fast-track research area worth mass attention." @default.
- W3143080003 created "2021-04-13" @default.
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- W3143080003 date "2012-01-01" @default.
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- W3143080003 title "Recent developments in mushrooms as anti-cancer therapeutics: a review" @default.
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