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- W3143141019 abstract "In order to investigate the genetic polymorphism of 13 cytokines genes in Han individuals from Zhejiang.The polymerase chain reaction-sequence specific primers(PCR-SSP) method was used to determine genetic polymorphisms in 100 unrelated healthy Han individuals from Zhejiang province.We found that:(1)The frequency of the TGFβ(G codon 25) allele is 1.00 and no TGFβ(C codon 25) allele is found.(2) The frequencies of IL-1α(C-889),IL-1β(C +3962),IL-4(T-1098),IL-6(G-174),IL-6(G nt565),IL-10(A-1082) and TNFα(G-238) alleles are more than 0.95;while the frequen-cies of IL-1α(T-889),IL-1α(T +3962),IL-4(G-1098),IL-6(A-174),IL-6(A nt565),IL-10(G-1082),TNFα(A-238) al-leles are less than 0.05.(3) The haplotype frequency of the high-producer-type GCC in IL-10 gene is 0.05,while the low-producer-type ATA is 0.735.The haplotype frequency of the high-producer-type TG in the TGFβ gene is 0.49,while the low-producer-type CC is 0.The hap lotype frequency of the high-producer-types AG and AA in the TNFα gene is 0.055,while of the low-producer-types GG and GA is 0.945.The results showed that the genetic polymorphism of cytokine genes in Han individuals from Zhejiang Province is distinctive." @default.
- W3143141019 created "2021-04-13" @default.
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- W3143141019 date "2007-01-01" @default.
- W3143141019 modified "2023-09-23" @default.
- W3143141019 title "The genetic polymorphism of cytokine genes in Zhejiang Han indi-viduals" @default.
- W3143141019 hasPublicationYear "2007" @default.
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