Matches in SemOpenAlex for { <https://semopenalex.org/work/W3143300178> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W3143300178 abstract "Objective To investigate the advantage and disadvantage of several methods often used to evaluate insulin resistance and to attempt to modify the disadvantage. Methods Three protocols of minimal model technique (MMT), three protocols of basal state approach and four protocols of oral glucose tolerance test (OGTT) were used respectively to calculate insulin sensitivity index (ISI) in 16 subjects with normal glucose tolerance (NGT) and 13 patients with noninsulindependent diabetes mellitus (NIDDM) . ISI of classical MMT was regarded as standard ; ISI of other protocols were analyzed, assessed and compared with that of classical MMT. Results Except the ISI expressed by the ratio of fasting serum glucose to insulin concentration (FSG/FIns)and the ratio between area under curve (AUC) of glucose and insulin (AUCg/AUCi) in OGTT, ISI of other protocols was significantly higher in NGT group than in NIDDM group (P0.05, ISI relative values were 1 and 0.440.70 respectively) and had stronger relationships as compared with ISI of classical MMT (r=0.450.92, P0.05). Conclusion The modifications that reduce the samples to 12 or 10 and shorten the time to 120 min for MMT are feasible. Both the homeostasis model assessment and the basal state method designed by LI Guangwei are very simple; they can roughly evaluate insulin sensitivity. OGTT designed by Cederholm is a relatively simple and precise method of measuring IR.Two protocols of OGTT designed by the authors may be accurate methods for evaluating IR. Both FSG/FIns and AUCg/AUCi can not reliably evaluate insulin sensitivity." @default.
- W3143300178 created "2021-04-13" @default.
- W3143300178 creator A5077955100 @default.
- W3143300178 creator A5084579042 @default.
- W3143300178 date "1999-01-01" @default.
- W3143300178 modified "2023-09-25" @default.
- W3143300178 title "A methodological study on the evaluation of insulin resistance in vivo" @default.
- W3143300178 hasPublicationYear "1999" @default.
- W3143300178 type Work @default.
- W3143300178 sameAs 3143300178 @default.
- W3143300178 citedByCount "0" @default.
- W3143300178 crossrefType "journal-article" @default.
- W3143300178 hasAuthorship W3143300178A5077955100 @default.
- W3143300178 hasAuthorship W3143300178A5084579042 @default.
- W3143300178 hasConcept C126322002 @default.
- W3143300178 hasConcept C134018914 @default.
- W3143300178 hasConcept C2777391703 @default.
- W3143300178 hasConcept C2778024521 @default.
- W3143300178 hasConcept C2779306644 @default.
- W3143300178 hasConcept C3017594256 @default.
- W3143300178 hasConcept C71924100 @default.
- W3143300178 hasConcept C76318530 @default.
- W3143300178 hasConceptScore W3143300178C126322002 @default.
- W3143300178 hasConceptScore W3143300178C134018914 @default.
- W3143300178 hasConceptScore W3143300178C2777391703 @default.
- W3143300178 hasConceptScore W3143300178C2778024521 @default.
- W3143300178 hasConceptScore W3143300178C2779306644 @default.
- W3143300178 hasConceptScore W3143300178C3017594256 @default.
- W3143300178 hasConceptScore W3143300178C71924100 @default.
- W3143300178 hasConceptScore W3143300178C76318530 @default.
- W3143300178 hasLocation W31433001781 @default.
- W3143300178 hasOpenAccess W3143300178 @default.
- W3143300178 hasPrimaryLocation W31433001781 @default.
- W3143300178 hasRelatedWork W1977535441 @default.
- W3143300178 hasRelatedWork W1981384500 @default.
- W3143300178 hasRelatedWork W1996010515 @default.
- W3143300178 hasRelatedWork W2033667814 @default.
- W3143300178 hasRelatedWork W2048018726 @default.
- W3143300178 hasRelatedWork W2052815692 @default.
- W3143300178 hasRelatedWork W2072214540 @default.
- W3143300178 hasRelatedWork W2091057636 @default.
- W3143300178 hasRelatedWork W2121648235 @default.
- W3143300178 hasRelatedWork W2292899397 @default.
- W3143300178 hasRelatedWork W2366706547 @default.
- W3143300178 hasRelatedWork W2372639249 @default.
- W3143300178 hasRelatedWork W2377567650 @default.
- W3143300178 hasRelatedWork W2418079233 @default.
- W3143300178 hasRelatedWork W2460836048 @default.
- W3143300178 hasRelatedWork W2460970605 @default.
- W3143300178 hasRelatedWork W2588353304 @default.
- W3143300178 hasRelatedWork W2609846814 @default.
- W3143300178 hasRelatedWork W2782366281 @default.
- W3143300178 hasRelatedWork W2977251457 @default.
- W3143300178 isParatext "false" @default.
- W3143300178 isRetracted "false" @default.
- W3143300178 magId "3143300178" @default.
- W3143300178 workType "article" @default.