FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3143313179> ?p ?o ?g. }

• W3143313179 endingPage "e0248898" @default.
• W3143313179 startingPage "e0248898" @default.
• W3143313179 abstract "Whereas time trends in the epidemiologic burden of US pediatric mental health disorders are well described, little is known about trends in how these disorders are studied through clinical research. We identified how funding source, disorders studied, treatments studied, and trial design changed over the past decade in US pediatric mental health clinical trials. We identified all US pediatric interventional mental health trials submitted to ClinicalTrials.gov between October 1, 2007 and April 30, 2018 (n = 1,019) and manually characterized disorders and treatments studied. We assessed trial growth and design characteristics by funding source, treatments, and disorders. US pediatric mental health trials grew over the past decade (compound annual growth rate [CAGR] 4.1%). The number of studies funded by industry and US government remained unchanged, whereas studies funded by other sources (e.g., academic medical centers) grew (CAGR 11.3%). Neurodevelopmental disorders comprised the largest proportion of disorders studied, and Non- DSM-5 ( Diagnostic and Statistical Manual-5 ) conditions was the only disorder category to grow (14.5% to 24.6%; first half to second half of decade). There was significant growth of trials studying non-psycho/pharmacotherapy treatments (33.8% to 49.0%) and a decline in trials studying pharmacotherapies (31.7% to 20.6%), though these trends differed by funding source. There were also notable differences in funding sources and treatments studied within each disorder category. Trials using double blinding declined (26.2% to 18.0%). Limitations include that ClinicalTrials.gov is not an exhaustive list of US clinical trials, and trends identified may in part reflect changes in trial registration rather than changes in clinical research. Nevertheless, ClinicalTrials.gov is among the largest databases available for evaluating trends and patterns in pediatric mental health research that might otherwise remain unassessable. Understanding these trends can guide researchers and funding bodies when considering the trajectory of the field." @default.
• W3143313179 created "2021-04-13" @default.
• W3143313179 creator A5011115329 @default.
• W3143313179 creator A5013838778 @default.
• W3143313179 creator A5021200670 @default.
• W3143313179 creator A5023644597 @default.
• W3143313179 creator A5025452931 @default.
• W3143313179 creator A5031963962 @default.
• W3143313179 creator A5061672466 @default.
• W3143313179 creator A5070358820 @default.
• W3143313179 creator A5083327006 @default.
• W3143313179 date "2021-04-01" @default.
• W3143313179 modified "2023-10-17" @default.
• W3143313179 title "Trends in US pediatric mental health clinical trials: An analysis of ClinicalTrials.gov from 2007–2018" @default.
• W3143313179 cites W1547319025 @default.
• W3143313179 cites W1970972270 @default.
• W3143313179 cites W1978560738 @default.
• W3143313179 cites W1982949981 @default.
• W3143313179 cites W1987866940 @default.
• W3143313179 cites W2003245298 @default.
• W3143313179 cites W2009875986 @default.
• W3143313179 cites W2017857169 @default.
• W3143313179 cites W2059796825 @default.
• W3143313179 cites W2064574930 @default.
• W3143313179 cites W2072710783 @default.
• W3143313179 cites W2085666676 @default.
• W3143313179 cites W2092025391 @default.
• W3143313179 cites W2093903966 @default.
• W3143313179 cites W2096526697 @default.
• W3143313179 cites W2101759344 @default.
• W3143313179 cites W2151428461 @default.
• W3143313179 cites W2155389918 @default.
• W3143313179 cites W2155920093 @default.
• W3143313179 cites W2238357926 @default.
• W3143313179 cites W2281553101 @default.
• W3143313179 cites W2466504929 @default.
• W3143313179 cites W2490038287 @default.
• W3143313179 cites W2545008233 @default.
• W3143313179 cites W2548970636 @default.
• W3143313179 cites W2581784150 @default.
• W3143313179 cites W2614349964 @default.
• W3143313179 cites W2736848882 @default.
• W3143313179 cites W2740187414 @default.
• W3143313179 cites W2741453912 @default.
• W3143313179 cites W2766907298 @default.
• W3143313179 cites W2781951191 @default.
• W3143313179 cites W2799338644 @default.
• W3143313179 cites W2804165413 @default.
• W3143313179 cites W2903069810 @default.
• W3143313179 cites W2964534932 @default.
• W3143313179 cites W2972163983 @default.
• W3143313179 cites W2987102569 @default.
• W3143313179 cites W3013038708 @default.
• W3143313179 cites W3033004471 @default.
• W3143313179 doi "https://doi.org/10.1371/journal.pone.0248898" @default.
• W3143313179 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8016324" @default.
• W3143313179 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33793587" @default.
• W3143313179 hasPublicationYear "2021" @default.
• W3143313179 type Work @default.
• W3143313179 sameAs 3143313179 @default.
• W3143313179 citedByCount "2" @default.
• W3143313179 countsByYear W31433131792022 @default.
• W3143313179 countsByYear W31433131792023 @default.
• W3143313179 crossrefType "journal-article" @default.
• W3143313179 hasAuthorship W3143313179A5011115329 @default.
• W3143313179 hasAuthorship W3143313179A5013838778 @default.
• W3143313179 hasAuthorship W3143313179A5021200670 @default.
• W3143313179 hasAuthorship W3143313179A5023644597 @default.
• W3143313179 hasAuthorship W3143313179A5025452931 @default.
• W3143313179 hasAuthorship W3143313179A5031963962 @default.
• W3143313179 hasAuthorship W3143313179A5061672466 @default.
• W3143313179 hasAuthorship W3143313179A5070358820 @default.
• W3143313179 hasAuthorship W3143313179A5083327006 @default.
• W3143313179 hasBestOaLocation W31433131791 @default.
• W3143313179 hasConcept C118552586 @default.
• W3143313179 hasConcept C126322002 @default.
• W3143313179 hasConcept C134362201 @default.
• W3143313179 hasConcept C17744445 @default.
• W3143313179 hasConcept C187212893 @default.
• W3143313179 hasConcept C199539241 @default.
• W3143313179 hasConcept C27415008 @default.
• W3143313179 hasConcept C2771230 @default.
• W3143313179 hasConcept C2779473830 @default.
• W3143313179 hasConcept C535046627 @default.
• W3143313179 hasConcept C71924100 @default.
• W3143313179 hasConceptScore W3143313179C118552586 @default.
• W3143313179 hasConceptScore W3143313179C126322002 @default.
• W3143313179 hasConceptScore W3143313179C134362201 @default.
• W3143313179 hasConceptScore W3143313179C17744445 @default.
• W3143313179 hasConceptScore W3143313179C187212893 @default.
• W3143313179 hasConceptScore W3143313179C199539241 @default.
• W3143313179 hasConceptScore W3143313179C27415008 @default.
• W3143313179 hasConceptScore W3143313179C2771230 @default.
• W3143313179 hasConceptScore W3143313179C2779473830 @default.
• W3143313179 hasConceptScore W3143313179C535046627 @default.
• W3143313179 hasConceptScore W3143313179C71924100 @default.
• W3143313179 hasIssue "4" @default.
• W3143313179 hasLocation W31433131791 @default.

• next