FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3143335972> ?p ?o ?g. }

• W3143335972 abstract "We review data available for treatment of multiple sclerosis (MS) before, during, and after pregnancy. We present recent data on disease-modifying therapies (DMT) before/during pregnancy and while breastfeeding, with treatment recommendations.Observational data support the safety of injectable DMTs (glatiramer acetate, interferon-beta) for use in pregnancy, while some oral DMTs might be associated with fetal risk. Monoclonal antibodies (mAbs) before pregnancy such as rituximab or natalizumab likely do not pose significant fetal risks, but can cross the placenta with neonatal hematological abnormalities if given in the second trimester or later. Breastfeeding is associated with decreased risk of postpartum relapses. Finally, injectables and mAbs likely have low transfer into breastmilk.Many women with MS do not require DMTs during pregnancy, although injectables could be continued. For women with highly active MS, cell-depleting therapies could be given before conception, or natalizumab could be continued through pregnancy, with monitoring of the fetus. Women should be encouraged to breastfeed, and those with higher relapse risk could consider injectables or mAbs while breastfeeding. Further data on safety of DMTs around pregnancy are needed. Maximizing function through non-pharmacologic approaches is complementary to DMTs. Special considerations for pregnancy and DMTs during the COVID-19 pandemic are needed." @default.
• W3143335972 created "2021-04-13" @default.
• W3143335972 creator A5016778416 @default.
• W3143335972 creator A5043996334 @default.
• W3143335972 creator A5051842646 @default.
• W3143335972 creator A5079021412 @default.
• W3143335972 creator A5088611035 @default.
• W3143335972 date "2021-03-30" @default.
• W3143335972 modified "2023-10-18" @default.
• W3143335972 title "Treatment of Women with Multiple Sclerosis Planning Pregnancy" @default.
• W3143335972 cites W1964937913 @default.
• W3143335972 cites W1977832740 @default.
• W3143335972 cites W1982437385 @default.
• W3143335972 cites W1987800960 @default.
• W3143335972 cites W1990261374 @default.
• W3143335972 cites W2016517137 @default.
• W3143335972 cites W2035248726 @default.
• W3143335972 cites W2035285899 @default.
• W3143335972 cites W2040969396 @default.
• W3143335972 cites W2045546162 @default.
• W3143335972 cites W2046481589 @default.
• W3143335972 cites W2054962526 @default.
• W3143335972 cites W2062256859 @default.
• W3143335972 cites W2072924355 @default.
• W3143335972 cites W2080252211 @default.
• W3143335972 cites W2080663859 @default.
• W3143335972 cites W2094515401 @default.
• W3143335972 cites W2095059461 @default.
• W3143335972 cites W2102986606 @default.
• W3143335972 cites W2110217905 @default.
• W3143335972 cites W2121412260 @default.
• W3143335972 cites W2124016103 @default.
• W3143335972 cites W2136577563 @default.
• W3143335972 cites W2142710970 @default.
• W3143335972 cites W2152684294 @default.
• W3143335972 cites W2157759118 @default.
• W3143335972 cites W2159592501 @default.
• W3143335972 cites W2189880526 @default.
• W3143335972 cites W2233092196 @default.
• W3143335972 cites W2319459971 @default.
• W3143335972 cites W2335803360 @default.
• W3143335972 cites W2336887160 @default.
• W3143335972 cites W2339959303 @default.
• W3143335972 cites W2345469235 @default.
• W3143335972 cites W2345592661 @default.
• W3143335972 cites W2404195341 @default.
• W3143335972 cites W2512790072 @default.
• W3143335972 cites W2565433170 @default.
• W3143335972 cites W2600773416 @default.
• W3143335972 cites W2614636769 @default.
• W3143335972 cites W2679979066 @default.
• W3143335972 cites W2751118480 @default.
• W3143335972 cites W2777074421 @default.
• W3143335972 cites W2786394311 @default.
• W3143335972 cites W2792505836 @default.
• W3143335972 cites W2794136267 @default.
• W3143335972 cites W2799594477 @default.
• W3143335972 cites W2805905738 @default.
• W3143335972 cites W2832364101 @default.
• W3143335972 cites W2894033169 @default.
• W3143335972 cites W2902426642 @default.
• W3143335972 cites W2902875236 @default.
• W3143335972 cites W2906840863 @default.
• W3143335972 cites W2918491388 @default.
• W3143335972 cites W2921754847 @default.
• W3143335972 cites W2940150523 @default.
• W3143335972 cites W2948438980 @default.
• W3143335972 cites W2985777739 @default.
• W3143335972 cites W2988019951 @default.
• W3143335972 cites W2994302013 @default.
• W3143335972 cites W2998731225 @default.
• W3143335972 cites W3005679569 @default.
• W3143335972 cites W3008159876 @default.
• W3143335972 cites W3008762759 @default.
• W3143335972 cites W3009721464 @default.
• W3143335972 cites W3015217151 @default.
• W3143335972 cites W3015607380 @default.
• W3143335972 cites W3016259199 @default.
• W3143335972 cites W3016273932 @default.
• W3143335972 cites W3017914220 @default.
• W3143335972 cites W3022375169 @default.
• W3143335972 cites W3023209915 @default.
• W3143335972 cites W3023795651 @default.
• W3143335972 cites W3024320461 @default.
• W3143335972 cites W3025929676 @default.
• W3143335972 cites W3027678838 @default.
• W3143335972 cites W3028001232 @default.
• W3143335972 cites W3028402548 @default.
• W3143335972 cites W3030419010 @default.
• W3143335972 cites W3030767837 @default.
• W3143335972 cites W4210343948 @default.
• W3143335972 cites W4212888212 @default.
• W3143335972 cites W4242575637 @default.
• W3143335972 cites W4249183247 @default.
• W3143335972 doi "https://doi.org/10.1007/s11940-021-00666-4" @default.
• W3143335972 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8008016" @default.
• W3143335972 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33814892" @default.
• W3143335972 hasPublicationYear "2021" @default.
• W3143335972 type Work @default.
• W3143335972 sameAs 3143335972 @default.

• next