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- W3143607609 abstract "Hypobaric hypoxic hypoxia conditions were simulated by raising mice in the altitude chamber to the level of 10,500-10,700 m. Enkephalin, its analogues, morphine and naloxone were injected once 1, 2, 3, 6 and 14 days prior to the experiment, and then their effects on stability to hypoxia were investigated depending on the time of drug administration. Only leu-enkephalin after a single injection was found to have antihypoxic properties for a week. Naloxone, but not phentolamine hydrochloride, blocked delayed antihypoxic effect of penta-peptide. Leu-enkephalin is thought to be endogenous antihypoxant." @default.
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- W3143607609 date "1988-05-01" @default.
- W3143607609 modified "2023-09-23" @default.
- W3143607609 title "[Delayed antihypoxic effect of leu enkephalin in mice]." @default.
- W3143607609 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3382733" @default.
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