Matches in SemOpenAlex for { <https://semopenalex.org/work/W3143647629> ?p ?o ?g. }
- W3143647629 endingPage "8220" @default.
- W3143647629 startingPage "8214" @default.
- W3143647629 abstract "Abstract DNA‐encoded combinatorial chemical library (DEL) technology, an approach that combines the power of genetics and chemistry, has emerged as an invaluable tool in drug discovery. Skeletal diversity plays a fundamental importance in DEL applications, and relies heavily on novel DNA‐compatible chemical reactions. We report herein a phylogenic chemical transformation strategy using DNA‐conjugated benzoyl hydrazine as a common versatile precursor in azole chemical expansion of DELs. DNA‐compatible reactions deriving from the common benzoyl hydrazine precursor showed excellent functional group tolerance with exceptional efficiency in the synthesis of various azoles, including oxadiazoles, thiadiazoles, and triazoles, under mild reaction conditions. The phylogenic chemical transformation strategy provides DELs a facile way to expand into various unique chemical spaces with privileged scaffolds and pharmacophores." @default.
- W3143647629 created "2021-04-13" @default.
- W3143647629 creator A5019575920 @default.
- W3143647629 creator A5030533811 @default.
- W3143647629 creator A5032135757 @default.
- W3143647629 creator A5038996015 @default.
- W3143647629 creator A5046875759 @default.
- W3143647629 creator A5047757264 @default.
- W3143647629 creator A5054521378 @default.
- W3143647629 creator A5064550740 @default.
- W3143647629 creator A5068252474 @default.
- W3143647629 creator A5069344375 @default.
- W3143647629 creator A5081400624 @default.
- W3143647629 date "2021-04-27" @default.
- W3143647629 modified "2023-10-11" @default.
- W3143647629 title "DNA‐Encoded Libraries: Hydrazide as a Pluripotent Precursor for On‐DNA Synthesis of Various Azole Derivatives" @default.
- W3143647629 cites W1968753037 @default.
- W3143647629 cites W1969173561 @default.
- W3143647629 cites W1980670485 @default.
- W3143647629 cites W1988011800 @default.
- W3143647629 cites W1991119675 @default.
- W3143647629 cites W1998634168 @default.
- W3143647629 cites W2004412820 @default.
- W3143647629 cites W2017423606 @default.
- W3143647629 cites W2017975422 @default.
- W3143647629 cites W2027043041 @default.
- W3143647629 cites W2028877284 @default.
- W3143647629 cites W2033059710 @default.
- W3143647629 cites W2045569554 @default.
- W3143647629 cites W2052925570 @default.
- W3143647629 cites W2068095506 @default.
- W3143647629 cites W2069397868 @default.
- W3143647629 cites W2075137974 @default.
- W3143647629 cites W2076765905 @default.
- W3143647629 cites W2086661635 @default.
- W3143647629 cites W2100590583 @default.
- W3143647629 cites W2125123585 @default.
- W3143647629 cites W2125368527 @default.
- W3143647629 cites W2126229929 @default.
- W3143647629 cites W2153561001 @default.
- W3143647629 cites W2156334594 @default.
- W3143647629 cites W2187828640 @default.
- W3143647629 cites W2299985318 @default.
- W3143647629 cites W2314446522 @default.
- W3143647629 cites W2321365024 @default.
- W3143647629 cites W2560677837 @default.
- W3143647629 cites W2577472120 @default.
- W3143647629 cites W2578775319 @default.
- W3143647629 cites W2584580415 @default.
- W3143647629 cites W2591004360 @default.
- W3143647629 cites W2592709654 @default.
- W3143647629 cites W2594586197 @default.
- W3143647629 cites W2619165690 @default.
- W3143647629 cites W2782995788 @default.
- W3143647629 cites W2809247499 @default.
- W3143647629 cites W2810724953 @default.
- W3143647629 cites W2938415036 @default.
- W3143647629 cites W2941297394 @default.
- W3143647629 cites W2941665192 @default.
- W3143647629 cites W2944513359 @default.
- W3143647629 cites W2949576014 @default.
- W3143647629 cites W2949676377 @default.
- W3143647629 cites W2950489603 @default.
- W3143647629 cites W2951527684 @default.
- W3143647629 cites W2952504204 @default.
- W3143647629 cites W2970782110 @default.
- W3143647629 cites W2978690934 @default.
- W3143647629 cites W2982660402 @default.
- W3143647629 cites W2983041080 @default.
- W3143647629 cites W2991587818 @default.
- W3143647629 cites W3011353733 @default.
- W3143647629 cites W3014301615 @default.
- W3143647629 cites W3014854122 @default.
- W3143647629 cites W3015229768 @default.
- W3143647629 cites W3083513001 @default.
- W3143647629 cites W4244913122 @default.
- W3143647629 cites W4251249919 @default.
- W3143647629 cites W589574422 @default.
- W3143647629 doi "https://doi.org/10.1002/chem.202100850" @default.
- W3143647629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33811386" @default.
- W3143647629 hasPublicationYear "2021" @default.
- W3143647629 type Work @default.
- W3143647629 sameAs 3143647629 @default.
- W3143647629 citedByCount "5" @default.
- W3143647629 countsByYear W31436476292021 @default.
- W3143647629 countsByYear W31436476292022 @default.
- W3143647629 countsByYear W31436476292023 @default.
- W3143647629 crossrefType "journal-article" @default.
- W3143647629 hasAuthorship W3143647629A5019575920 @default.
- W3143647629 hasAuthorship W3143647629A5030533811 @default.
- W3143647629 hasAuthorship W3143647629A5032135757 @default.
- W3143647629 hasAuthorship W3143647629A5038996015 @default.
- W3143647629 hasAuthorship W3143647629A5046875759 @default.
- W3143647629 hasAuthorship W3143647629A5047757264 @default.
- W3143647629 hasAuthorship W3143647629A5054521378 @default.
- W3143647629 hasAuthorship W3143647629A5064550740 @default.
- W3143647629 hasAuthorship W3143647629A5068252474 @default.
- W3143647629 hasAuthorship W3143647629A5069344375 @default.