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• W3143663775 abstract "The attachment and proliferation of a well-established, neuron-like cell line, rat pheochro- mocytoma (PC12) cells, on different extracellular matrices (ECMs) was monitored using cellular imped- ance sensing (CIS). Commonly used ECMs, including fibronectin, laminin, poly-L-lysine, collagen and poly- L-lysine followed by laminin, in addition to DMEM cell culture media alone as a control, were studied: CIS identified the dynamic progress of the adhesion and proliferation of the cells on different ECMs. Among these modified ECM surfaces, the laminin- and poly-L- lysine/laminin-modified surfaces were the best suited for the neuron-to-electrode surface attachment and proliferation, which was confirmed by MTT assays and a scanning electron microscopy analysis. This work provides a simple method to study neuron cell/ ECM interactions in a real-time, label-free, and quantitative manner." @default.
• W3143663775 created "2021-04-13" @default.
• W3143663775 creator A5007730940 @default.
• W3143663775 date "2012-01-01" @default.
• W3143663775 modified "2023-09-27" @default.
• W3143663775 title "Real-time monitoring of extracellular matrix-mediated PC12 cell attachment and proliferation using an electronic biosensing device" @default.
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• W3143663775 hasPublicationYear "2012" @default.
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