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- W3143672904 abstract "The chromatin structure is dynamically regulated by many different modulators that post-translationally modify histones, replace canonical histones with histone variants, and unwind nucleosomal DNA, thereby modulating the accessibility of nucleosomal DNA and facilitating downstream DNA-templated nuclear processes. To understand how these modulators change the chromatin structure, it is essential to determine the 3D structures of chromatin modulators in complex with nucleosome. Here, we review the very recent progress in structural studies of some selected chromatin modulators in complex with nucleosome, including those of histone demethylases LSD1/2, some pioneer transcription factors, and the PWWP domain–containing protein LEDGF." @default.
- W3143672904 created "2021-04-13" @default.
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- W3143672904 date "2021-08-01" @default.
- W3143672904 modified "2023-09-24" @default.
- W3143672904 title "Structures of chromatin modulators in complex with nucleosome" @default.
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- W3143672904 doi "https://doi.org/10.1016/j.cbpa.2021.02.018" @default.
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