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- W3143679010 abstract "Chemotherapy-induced nausea and vomiting (CINV) is one of the most unpleasant non-haematological side effects that affects a patient's quality of life and leads to poor adherence to further chemotherapy. The current antiemetic guidelines recommend a three-drug combination of a 5-HT3 receptor antagonist, dexamethasone, and aprepitant for patients undergoing highly emetogenic chemotherapy. However, the efficacy of aprepitant has not been well investigated in breast cancer patients receiving doxorubicin and cyclophosphamide (AC). We investigated the incidence of nausea and vomiting before and after the introduction of aprepitant therapy in breast cancer patients. In addition, we also attempted to identify the risk factors predisposing these patients to CINV development." @default.
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- W3143679010 date "2017-01-01" @default.
- W3143679010 modified "2023-10-06" @default.
- W3143679010 title "Comparative Investigation of the Antiemetic Efficacy of Aprepitant Containing Antiemetic Regimen in Breast Cancer Patients Receiving Doxorubicin and Cyclophosphamide Combination Chemotherapy" @default.
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- W3143679010 doi "https://doi.org/10.5649/jjphcs.43.1" @default.
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