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• W3143768062 abstract "This study demonstrates the screening of a collection of twelve 19F-tagged metal-binding pharmacophores (MBPs) against the Zn(ii)-dependent metalloenzyme human carbonic anhydrase II (hCAII) by 19F NMR. The isomorphous replacement of Zn(ii) by Co(ii) in hCAII produces enhanced sensitivity and reveals the potential of 19F NMR-based techniques for metalloenzyme ligand discovery." @default.
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• W3143768062 date "2021-01-01" @default.
• W3143768062 modified "2023-10-09" @default.
• W3143768062 title "¹⁹F-Tagged metal binding pharmacophores for NMR screening of metalloenzymes" @default.
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• W3143768062 doi "https://doi.org/10.1039/d1cc01231b" @default.
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