Matches in SemOpenAlex for { <https://semopenalex.org/work/W3143842015> ?p ?o ?g. }
- W3143842015 abstract "Preeclampsia is a multiorgan disorder associated with maternal and perinatal morbi-mortality. In Peru, incidence is 10% and accounts for 22% of maternal deaths. Genome and genetic epidemiological studies have found an association between preeclampsia and genetic polymorphisms.To determine the association of the vascular endothelial growth factor (VEGF) +936 C/T and +405 G/C, interleukine-6 (IL-6) -174 G/C, IL-1β-511 C/T, Apo A-1-75 G/A, Apo B-100 2488 C/T (Xbal) polymorphisms with preeclampsia in pregnant Peruvian women.Were included preeclamptic and healthy (control) pregnant women. Maternal blood samples were subjected to DNA extraction, and molecular genetic analysis was conducted using the PCR-RFLP technique and following a specific protocol for each gene. Allele and genotypic frequencies in the cases and controls were compared.No association was found between the VEGF+936C/T and VEGF+405 polymorphisms and preeclampsia. The frequencies of the GG genotypes and the G allele of the -174 G/C polymorphism in the IL6 gene in preeclamptic and controls showed significant differences, with higher frequencies in cases. For the -511 C/T polymorphism of the IL-1β gene, no significant differences were found in the frequencies of TT genotypes compared with CT+CC. The genotypes and alleles of the Apo-A1-75 G/A and Apo-B100 Xbal variants showed no significant differences between cases and controls.No association was found between the studied genetic markers and preeclampsia. However, in the -174G/C polymorphism of the IL-6 gene, significant differences were found mainly in the GG genotype and G allele." @default.
- W3143842015 created "2021-04-13" @default.
- W3143842015 creator A5012740496 @default.
- W3143842015 creator A5021778626 @default.
- W3143842015 creator A5026301713 @default.
- W3143842015 creator A5026312443 @default.
- W3143842015 creator A5050212791 @default.
- W3143842015 creator A5053562964 @default.
- W3143842015 creator A5056484860 @default.
- W3143842015 creator A5062449513 @default.
- W3143842015 creator A5066233242 @default.
- W3143842015 creator A5070865122 @default.
- W3143842015 creator A5073954209 @default.
- W3143842015 creator A5079907344 @default.
- W3143842015 creator A5084504782 @default.
- W3143842015 creator A5087963407 @default.
- W3143842015 creator A5087986073 @default.
- W3143842015 creator A5088844267 @default.
- W3143842015 creator A5089586571 @default.
- W3143842015 date "2020-07-07" @default.
- W3143842015 modified "2023-09-26" @default.
- W3143842015 title "Genetic markers for preeclampsia in Peruvian women" @default.
- W3143842015 cites W1416304121 @default.
- W3143842015 cites W1538951249 @default.
- W3143842015 cites W168133812 @default.
- W3143842015 cites W1769239105 @default.
- W3143842015 cites W1920171370 @default.
- W3143842015 cites W1965939872 @default.
- W3143842015 cites W1967420987 @default.
- W3143842015 cites W1970874206 @default.
- W3143842015 cites W1976872557 @default.
- W3143842015 cites W1977798837 @default.
- W3143842015 cites W1977819701 @default.
- W3143842015 cites W1980023741 @default.
- W3143842015 cites W1982487925 @default.
- W3143842015 cites W1982627213 @default.
- W3143842015 cites W1987358907 @default.
- W3143842015 cites W1990005924 @default.
- W3143842015 cites W1992723769 @default.
- W3143842015 cites W1992978123 @default.
- W3143842015 cites W1999005255 @default.
- W3143842015 cites W2000957632 @default.
- W3143842015 cites W2002521044 @default.
- W3143842015 cites W2008638430 @default.
- W3143842015 cites W2008752479 @default.
- W3143842015 cites W2009381676 @default.
- W3143842015 cites W2012486372 @default.
- W3143842015 cites W2015327546 @default.
- W3143842015 cites W2018067729 @default.
- W3143842015 cites W2024650492 @default.
- W3143842015 cites W2028054693 @default.
- W3143842015 cites W2034351432 @default.
- W3143842015 cites W2034852655 @default.
- W3143842015 cites W2037914543 @default.
- W3143842015 cites W2039163567 @default.
- W3143842015 cites W2042863269 @default.
- W3143842015 cites W2043007266 @default.
- W3143842015 cites W2047191881 @default.
- W3143842015 cites W2047478159 @default.
- W3143842015 cites W2051455132 @default.
- W3143842015 cites W2064387196 @default.
- W3143842015 cites W2080112868 @default.
- W3143842015 cites W2081876722 @default.
- W3143842015 cites W2084223732 @default.
- W3143842015 cites W2089109912 @default.
- W3143842015 cites W2090552703 @default.
- W3143842015 cites W2101770889 @default.
- W3143842015 cites W2102981125 @default.
- W3143842015 cites W2104468961 @default.
- W3143842015 cites W2104626076 @default.
- W3143842015 cites W2105570266 @default.
- W3143842015 cites W2109978768 @default.
- W3143842015 cites W2112976182 @default.
- W3143842015 cites W2118387070 @default.
- W3143842015 cites W2119500425 @default.
- W3143842015 cites W2121387927 @default.
- W3143842015 cites W2122154463 @default.
- W3143842015 cites W2124526671 @default.
- W3143842015 cites W2132961242 @default.
- W3143842015 cites W2151955795 @default.
- W3143842015 cites W2161738289 @default.
- W3143842015 cites W2163444047 @default.
- W3143842015 cites W2166952082 @default.
- W3143842015 cites W2167267303 @default.
- W3143842015 cites W2168064204 @default.
- W3143842015 cites W2253587663 @default.
- W3143842015 cites W2290324068 @default.
- W3143842015 cites W2317841552 @default.
- W3143842015 cites W2321513766 @default.
- W3143842015 cites W2335445958 @default.
- W3143842015 cites W2336698198 @default.
- W3143842015 cites W2341980020 @default.
- W3143842015 cites W2419949556 @default.
- W3143842015 cites W2521278162 @default.
- W3143842015 cites W2546986263 @default.
- W3143842015 cites W2587693305 @default.
- W3143842015 cites W2592511852 @default.
- W3143842015 cites W2611400576 @default.
- W3143842015 cites W2754058454 @default.
- W3143842015 cites W2776302256 @default.