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- W3143946661 abstract "BACKGROUNDAortic input impedance is altered in patients with congestive heart failure. However, little is known about whether this vascular response is an early change or a late manifestation of left ventricular dysfunction.METHODS AND RESULTSThis investigation used a paced canine model of congestive heart failure to demonstrate that abnormal aortic input impedance does evolve in the setting of ventricular systolic dysfunction and to prospectively define the time course of change in aortic input impedance and conduit vessel compliance. Studies were performed in closed-chest conditioned beagles aged 1 to 2 years that underwent hemodynamic evaluation at baseline and after induction of left ventricular dysfunction by rapid ventricular pacing. Within 48 hours of the onset of rapid ventricular pacing, we observed mild left ventricular systolic dysfunction with an echocardiographically derived left ventricular ejection fraction of 37% (p < .001 compared with baseline) measured during interruption of rapid ventr..." @default.
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- W3143946661 date "1993-01-01" @default.
- W3143946661 modified "2023-09-24" @default.
- W3143946661 title "Increased aortic impedance precedes peripheral vasoconstriction at the early stage of ventricular failure in the paced canine model." @default.
- W3143946661 hasPublicationYear "1993" @default.
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