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- W3143991143 endingPage "183619" @default.
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- W3143991143 abstract "The human colon balances water and electrolyte absorption and secretion while also forming a barrier protecting the body from the entry of harmful components. Aquaporin-3 (AQP3) is a water, glycerol and H 2 O 2 transporting channel expressed in colonic epithelia. Although expression of colonic epithelial AQP3 is altered in several intestinal disorders, such as inflammatory bowel disease and irritable bowel syndrome, the regulation and specific roles of AQP3 remain to be fully defined. In this mini-review, we summarize the current understanding of the expression, regulation, and biological functions of AQP3 protein in colonic epithelia concerning intestinal absorption, secretion and barrier function. • Aquaporin 3 is expressed in colonic epithelial cells • Altered aquaporin 3 expression affects epithelial tight junction integrity and permeability • Expression of aquaporin 3 is altered in various disease states in the colon" @default.
- W3143991143 created "2021-04-13" @default.
- W3143991143 creator A5032266747 @default.
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- W3143991143 date "2021-07-01" @default.
- W3143991143 modified "2023-09-26" @default.
- W3143991143 title "Expression, regulation and function of Aquaporin-3 in colonic epithelial cells" @default.
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- W3143991143 doi "https://doi.org/10.1016/j.bbamem.2021.183619" @default.
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