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- W3144001512 abstract "Summc~ry. The well-known histochemical reactivity of asbestos bodies has been modified by treatment with iron extracting solutions and enzymes. Asbestos bodies did not exhibit any more Prussian blue pasitivity after treatment with iron extract ing solutions, but showed a toluidine blue metachromasia due to hyaluronic acid. The same bodies, treated before with iron removing solutions and digested with testicular hyaluronidase, were not to!uidine blue metachromatic, but exhibited again a Perls positivity. Then these same bodies became agairt Perls negative after a second iron extraction, and showed instead a positive hematoidin reaction. The diameter of the same body appeared progressively smaller after each treatment. Moreover the hematoidin positive layer had been so digested by trypsin that asbestos fibres were at least optically naked. These findings suggest that during the development of asbestos body coating, first proteins, hematoidin and ferric iron are deposited over asbestos fibres; subsequently hyaluronie acid is laid around the first layer, and finally other ferric iron particles impregnate the hyaluronic acid molecules." @default.
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- W3144001512 date "1972-01-01" @default.
- W3144001512 modified "2023-09-26" @default.
- W3144001512 title "Histochemical Demonstration of Hematoidin in the Innermost Layers of Human Asbestos Body Coating" @default.
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