Matches in SemOpenAlex for { <https://semopenalex.org/work/W3144095627> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W3144095627 endingPage "857" @default.
- W3144095627 startingPage "850" @default.
- W3144095627 abstract "组蛋白甲基化是参予细胞的过程的一个多样的数组的重要 epigenetic 现象并且被发现了与癌症被联系。几的 Recentidentification 嘘一 demethylases 证明了那嘘一甲基化是一个可逆过程。通过一条候选人途径，我们化学上有简历作为 H3K27demethylase 识别了 JMJD3。进 HeLa 房间的 JMJD3 的 Transfection 引起了整齐的乙醇 H3K27 的特定的减小，但是没在 di- 和单音的甲基 H3K27 上有效果，或嘘 H3K4 和 H3K9 上的一离氨酸 methylations。Theenzymatic 活动要求 JmjC 域和被建议了为余因子绑定重要的保存组氨酸。试管内生物化学的实验证明那 JMJD3directly 催化 demethylation。另外，我们发现 JMJD3 起来在前列腺癌症，和它的表示调整了在变形前列腺癌症是更高的。因此，我们作为能够把整齐的乙醇组从移开的 ademethylase 识别了 JMJD3 嘘一 H3 离氨酸 27 并且起来在前列腺癌症调整了。" @default.
- W3144095627 created "2021-04-13" @default.
- W3144095627 creator A5008108990 @default.
- W3144095627 creator A5011605417 @default.
- W3144095627 creator A5016891658 @default.
- W3144095627 creator A5019388828 @default.
- W3144095627 creator A5024060626 @default.
- W3144095627 creator A5031574504 @default.
- W3144095627 creator A5036457690 @default.
- W3144095627 creator A5042979418 @default.
- W3144095627 creator A5049316498 @default.
- W3144095627 creator A5049758870 @default.
- W3144095627 creator A5068607867 @default.
- W3144095627 creator A5073161777 @default.
- W3144095627 creator A5083320053 @default.
- W3144095627 date "2007-01-01" @default.
- W3144095627 modified "2023-09-23" @default.
- W3144095627 title "JMJD3 is a histone H3K27 demethylase" @default.
- W3144095627 hasPublicationYear "2007" @default.
- W3144095627 type Work @default.
- W3144095627 sameAs 3144095627 @default.
- W3144095627 citedByCount "0" @default.
- W3144095627 crossrefType "journal-article" @default.
- W3144095627 hasAuthorship W3144095627A5008108990 @default.
- W3144095627 hasAuthorship W3144095627A5011605417 @default.
- W3144095627 hasAuthorship W3144095627A5016891658 @default.
- W3144095627 hasAuthorship W3144095627A5019388828 @default.
- W3144095627 hasAuthorship W3144095627A5024060626 @default.
- W3144095627 hasAuthorship W3144095627A5031574504 @default.
- W3144095627 hasAuthorship W3144095627A5036457690 @default.
- W3144095627 hasAuthorship W3144095627A5042979418 @default.
- W3144095627 hasAuthorship W3144095627A5049316498 @default.
- W3144095627 hasAuthorship W3144095627A5049758870 @default.
- W3144095627 hasAuthorship W3144095627A5068607867 @default.
- W3144095627 hasAuthorship W3144095627A5073161777 @default.
- W3144095627 hasAuthorship W3144095627A5083320053 @default.
- W3144095627 hasConcept C104317684 @default.
- W3144095627 hasConcept C185592680 @default.
- W3144095627 hasConcept C2776745794 @default.
- W3144095627 hasConcept C2781364455 @default.
- W3144095627 hasConcept C41091548 @default.
- W3144095627 hasConcept C54355233 @default.
- W3144095627 hasConcept C55493867 @default.
- W3144095627 hasConcept C64927066 @default.
- W3144095627 hasConcept C86803240 @default.
- W3144095627 hasConceptScore W3144095627C104317684 @default.
- W3144095627 hasConceptScore W3144095627C185592680 @default.
- W3144095627 hasConceptScore W3144095627C2776745794 @default.
- W3144095627 hasConceptScore W3144095627C2781364455 @default.
- W3144095627 hasConceptScore W3144095627C41091548 @default.
- W3144095627 hasConceptScore W3144095627C54355233 @default.
- W3144095627 hasConceptScore W3144095627C55493867 @default.
- W3144095627 hasConceptScore W3144095627C64927066 @default.
- W3144095627 hasConceptScore W3144095627C86803240 @default.
- W3144095627 hasIssue "10" @default.
- W3144095627 hasLocation W31440956271 @default.
- W3144095627 hasOpenAccess W3144095627 @default.
- W3144095627 hasPrimaryLocation W31440956271 @default.
- W3144095627 hasRelatedWork W1971180847 @default.
- W3144095627 hasRelatedWork W1998547735 @default.
- W3144095627 hasRelatedWork W2022702689 @default.
- W3144095627 hasRelatedWork W2071255786 @default.
- W3144095627 hasRelatedWork W2077981176 @default.
- W3144095627 hasRelatedWork W2080585376 @default.
- W3144095627 hasRelatedWork W2086184439 @default.
- W3144095627 hasRelatedWork W2086554513 @default.
- W3144095627 hasRelatedWork W2185909429 @default.
- W3144095627 hasRelatedWork W2260356139 @default.
- W3144095627 hasRelatedWork W2347936364 @default.
- W3144095627 hasRelatedWork W2407824668 @default.
- W3144095627 hasRelatedWork W2597060499 @default.
- W3144095627 hasRelatedWork W2739741429 @default.
- W3144095627 hasRelatedWork W2797045064 @default.
- W3144095627 hasRelatedWork W288456051 @default.
- W3144095627 hasRelatedWork W2889508766 @default.
- W3144095627 hasRelatedWork W640349561 @default.
- W3144095627 hasRelatedWork W2521222051 @default.
- W3144095627 hasRelatedWork W2620855617 @default.
- W3144095627 hasVolume "17" @default.
- W3144095627 isParatext "false" @default.
- W3144095627 isRetracted "false" @default.
- W3144095627 magId "3144095627" @default.
- W3144095627 workType "article" @default.