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- W3144201735 abstract "胃的酸在消化食物(特别蛋白质) 起一个重要作用,铁吸收,和破坏咽下的微生物。H+ 被泌酸壁细胞分泌,它的分泌物被 endocrine,神经分泌的和 paracrine 机制调整。免除窦 G 房间的促胃液素是胃的酸分泌物的主要生理的刺激。象 enterochromaffin 一样(ECL ) 的激活房间作为参予酸分泌物的规定的组织安的主要来源被接受并且是机能上地并且营养的联盟者由促胃液素控制了,它被在 ECL 房间上表示的 gastrin/CCK-2 受体调停。然而,长期的 hypergastrinemia 将导致 ECL 房间增生并且可能良性肿瘤。临床上,酸分泌物的有势力禁止者与酸相关的混乱广泛地被规定了到病人。长期的有势力酸抑制在血浆促胃液素层次唤起显著增加,导致有 ECL 房间增生的泌酸粘膜的增大。因此, ECL 房间增生和良性肿瘤的正式就职仍然是可观的担心的一个话题,特别在长期的使用。另外, ECL 房间的激活也导致另一颗临床的担心,即,在酸抑制以后的反弹酸分泌过盛。最近的试验性、临床的调查结果显示 ECL 房间的激活两个都起一个关键作用生理的联盟者并且临床上在胃的酸的规定分泌物。" @default.
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- W3144201735 date "2007-01-01" @default.
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- W3144201735 title "Physiological and clinical significance of enterochromaffin-like cell activation in the regulation of gastric acid secretion" @default.
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