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- W3144320303 abstract "Introduction: In patients of hepatocellular carcinoma (HCC) with good liver function and without vascular or extra-hapatic metastasis, hepatectomy or non surgical therapies such as radiofrequency ablation and transcatheter arterial chemo-embolization are recommended. However, non surgical therapies may cause local recurrence, and the recurrence may repeatedly be treated non-surgically, and finally vascular invasion or extrahepatic metastasis may occur. In such cases, definitive therapy is only hepatectomy, which is called salvage surgery. But it's pros and cons of this salvage surgery are still unclear. Methods: Between April 2010 and December 2018, 274 patients underwent hepatectomy for HCC at our institution. Out of 10 patients who underwent non-surgical therapies for more than 2 years before hepatectomy, 8 patients who recurred with vascular invasion were enrolled in this study. Results: The median survival duration after hepatectomy was 13.5 months, and the 1- and 3-year survival rates were 62 % and 37.5 %, respectively. Six patients died because of recurrence or extra-hepatic metastases. The median postoperative hospital stay was 20 days (11-44) and the perioperative mortality was 0%. Complications of Clavien-Dindo Class Ⅲa and Ⅲb were observed in 4 patients (bile fistula, postoperative bleeding). Conclusion: Although liver function is often deteriorated in recurrent cases with vascular invasion after long-term non-surgical therapies against HCC, salvage surgery can be safely performed by adding preoperative treatments such as portal vein embolization, and may lead better prognosis." @default.
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- W3144320303 date "2021-01-01" @default.
- W3144320303 modified "2023-10-16" @default.
- W3144320303 title "Efficacy of Salvage Surgery for HCC Recurred with Vascular Invasion after Long-term Non-surgical Therapies" @default.
- W3144320303 doi "https://doi.org/10.1016/j.hpb.2020.11.399" @default.
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