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- W3144372722 abstract "Objective To investigate the effect of high power microwave(HPM)radiation on morphology of liver cells and serum cytokines in rats.Methods Adult male Wistar rats were exposed to 100mW/cm2 intensity microwave radiation as experimental group,and rats without radiation were designed as normal controls.The blood samples were obtained from the hearts to determine the levels of aspartate transaminase(AST),alanine aminotransferase(ALT),interleukin(IL)-6,IL-10and IL-18on 1d,7dand 14dafter HPM radiation.Finally the rats were sacrificed and the right leaf tissues of liver were obtained immediately under ice bath,and the hepatic tissue changes were observed under routine light microscope.Results There were inflammatory cell infiltration,scattered,and patched cell degradation,and necrosis in rat hepatic lobule on1dand 7dafter HPM radiation;the situation was improved on 14dafter radiation,but there were still cell degradation and dotted necrosis.Serum levels of AST and ALT in the experimental group were significantly higher than those in the control group on 1dand 7dafter HPM radiation(P0.05,P0.01),but not on 14dafter radiation(P0.05).Serum levels of cytokines IL-6and IL-18in the experimental group were significantly higher than those in the control group on 1dand 7d after HPM radiation(P0.01),and the changes recovered somewhat on 14dafter radiation.Level of IL-10was decreasedafter radiation compared with the control group,with significant difference found on 1 dafter radiation(P 0.05).Conclusion HPM radiation can cause damage to liver structure and function,which might be associated with the changes of serum IL-6,IL-10and IL-18levels." @default.
- W3144372722 created "2021-04-13" @default.
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- W3144372722 date "2014-01-01" @default.
- W3144372722 modified "2023-09-28" @default.
- W3144372722 title "Effect of high power microwave radiation on liver injury and serum cytokine in rats" @default.
- W3144372722 hasPublicationYear "2014" @default.
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