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- W3144487912 abstract "Hypothalamic histaminergic tuberomammillary (TM ) 神经原表示烟碱的醋胆素受体(nAChRs ) 与运动并且类似于那些的药理学性质高度 Ca2+ 可渗透 7 nAChRs。然而， TM nAChR 隧道的 Ca2+ 渗透一直不是坚定的。直接评估 TM nAChRs 的 Ca2+ 渗透，补丁夹钳记录用包含的非有教养的尖锐地分裂的 TM 神经原和外部答案被进行低(2 公里) 并且高度(20 公里)Ca2+ 的集中。在颠倒潜力的移动从 currentvoltage 关系和渗透比率被决定， PCa/PNa，在 Goldman-Hodgkin-Katz 经常的地近似以内被估计。TM nAChRs 被发现是高度与渗透比率可渗透的 Ca2+ ，是的 PCa/PNa (nAChR ) 5.9 并且部分 Ca2+ 水流， Pf (nAChR )10.1% 在 ? 60 mV。作为为应用方法和分析的积极控制，渗透比率， PCa/PNa ( NMDAR )是 8.3 并且部分Ca2+水流， Pf ( NMDAR )是13.6%在?为 NMDA 受体的 60 mV 用非有教养的尖锐地分裂的海马趾的金字塔形的神经原被决定并且成立类似于以前报导的价值。因此，这些结果证明本国的 TM nAChRs 是高度 Ca2+ 可渗透，但是对 Ca2+ 可渗透的 1.4 褶层更少比本国的海马趾的金字塔形的 NMDA 受体。" @default.
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- W3144487912 date "2010-01-01" @default.
- W3144487912 modified "2023-09-24" @default.
- W3144487912 title "Evaluation of Ca2＋ permeability of nicotinic acetylcholine receptors in hypothalamic histaminergic neurons" @default.
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