FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3144644328> ?p ?o ?g. }

• W3144644328 endingPage "1942" @default.
• W3144644328 startingPage "1942" @default.
• W3144644328 abstract "Porphyrinic compounds are widespread in nature and play key roles in biological processes such as oxygen transport in blood, enzymatic redox reactions or photosynthesis. In addition, both naturally derived as well as synthetic porphyrinic compounds are extensively explored for biomedical and technical applications such as photodynamic therapy (PDT) or photovoltaic systems, respectively. Their unique electronic structures and photophysical properties make this class of compounds so interesting for the multiple functions encountered. It is therefore not surprising that optical methods are typically the prevalent analytical tool applied in characterization and processes involving porphyrinic compounds. However, a wealth of complementary information can be obtained from NMR spectroscopic techniques. Based on the advantage of providing structural and dynamic information with atomic resolution simultaneously, NMR spectroscopy is a powerful method for studying molecular interactions between porphyrinic compounds and macromolecules. Such interactions are of special interest in medical applications of porphyrinic photosensitizers that are mostly combined with macromolecular carrier systems. The macromolecular surrounding typically stabilizes the encapsulated drug and may also modify its physical properties. Moreover, the interaction with macromolecular physiological components needs to be explored to understand and control mechanisms of action and therapeutic efficacy. This review focuses on such non-covalent interactions of porphyrinic drugs with synthetic polymers as well as with biomolecules such as phospholipids or proteins. A brief introduction into various NMR spectroscopic techniques is given including chemical shift perturbation methods, NOE enhancement spectroscopy, relaxation time measurements and diffusion-ordered spectroscopy. How these NMR tools are used to address porphyrin–macromolecule interactions with respect to their function in biomedical applications is the central point of the current review." @default.
• W3144644328 created "2021-04-13" @default.
• W3144644328 creator A5039630514 @default.
• W3144644328 creator A5044721198 @default.
• W3144644328 creator A5071357234 @default.
• W3144644328 date "2021-03-30" @default.
• W3144644328 modified "2023-09-30" @default.
• W3144644328 title "Probing the Interactions of Porphyrins with Macromolecules Using NMR Spectroscopy Techniques" @default.
• W3144644328 cites W1153897568 @default.
• W3144644328 cites W1964615485 @default.
• W3144644328 cites W1964757697 @default.
• W3144644328 cites W1965306364 @default.
• W3144644328 cites W1965918908 @default.
• W3144644328 cites W1968509850 @default.
• W3144644328 cites W1969823401 @default.
• W3144644328 cites W1969885133 @default.
• W3144644328 cites W1970977546 @default.
• W3144644328 cites W1971666978 @default.
• W3144644328 cites W1971718186 @default.
• W3144644328 cites W1971817705 @default.
• W3144644328 cites W1974601383 @default.
• W3144644328 cites W1976008991 @default.
• W3144644328 cites W1978743038 @default.
• W3144644328 cites W1979744367 @default.
• W3144644328 cites W1979993712 @default.
• W3144644328 cites W1980797067 @default.
• W3144644328 cites W1982947517 @default.
• W3144644328 cites W1983057237 @default.
• W3144644328 cites W1984468583 @default.
• W3144644328 cites W1988680835 @default.
• W3144644328 cites W1989607288 @default.
• W3144644328 cites W1989643618 @default.
• W3144644328 cites W1990426276 @default.
• W3144644328 cites W1990719397 @default.
• W3144644328 cites W1991083456 @default.
• W3144644328 cites W1992181634 @default.
• W3144644328 cites W1992960527 @default.
• W3144644328 cites W1995246097 @default.
• W3144644328 cites W1995684657 @default.
• W3144644328 cites W1996911308 @default.
• W3144644328 cites W1997159232 @default.
• W3144644328 cites W1997419062 @default.
• W3144644328 cites W1998118539 @default.
• W3144644328 cites W1998982814 @default.
• W3144644328 cites W2000934453 @default.
• W3144644328 cites W2002726621 @default.
• W3144644328 cites W2004069235 @default.
• W3144644328 cites W2004867370 @default.
• W3144644328 cites W2005467831 @default.
• W3144644328 cites W2005672363 @default.
• W3144644328 cites W2009369127 @default.
• W3144644328 cites W2011573341 @default.
• W3144644328 cites W2011696455 @default.
• W3144644328 cites W2012630683 @default.
• W3144644328 cites W2016294761 @default.
• W3144644328 cites W2018538207 @default.
• W3144644328 cites W2021263337 @default.
• W3144644328 cites W2022026250 @default.
• W3144644328 cites W2022610406 @default.
• W3144644328 cites W2023031272 @default.
• W3144644328 cites W2023801036 @default.
• W3144644328 cites W2023991976 @default.
• W3144644328 cites W2026889493 @default.
• W3144644328 cites W2028737713 @default.
• W3144644328 cites W2030351885 @default.
• W3144644328 cites W2030721645 @default.
• W3144644328 cites W2031781185 @default.
• W3144644328 cites W2035950214 @default.
• W3144644328 cites W2036459378 @default.
• W3144644328 cites W2037918688 @default.
• W3144644328 cites W2038379895 @default.
• W3144644328 cites W2038984689 @default.
• W3144644328 cites W2039346519 @default.
• W3144644328 cites W2039639793 @default.
• W3144644328 cites W2043480650 @default.
• W3144644328 cites W2043587863 @default.
• W3144644328 cites W2044466451 @default.
• W3144644328 cites W2044899652 @default.
• W3144644328 cites W2045446885 @default.
• W3144644328 cites W2048165214 @default.
• W3144644328 cites W2051023674 @default.
• W3144644328 cites W2052912107 @default.
• W3144644328 cites W2053769869 @default.
• W3144644328 cites W2053799041 @default.
• W3144644328 cites W2055875086 @default.
• W3144644328 cites W2056903291 @default.
• W3144644328 cites W2058575034 @default.
• W3144644328 cites W2058634067 @default.
• W3144644328 cites W2059998193 @default.
• W3144644328 cites W2060922255 @default.
• W3144644328 cites W2061591904 @default.
• W3144644328 cites W2071705695 @default.
• W3144644328 cites W2072293604 @default.
• W3144644328 cites W2073028439 @default.
• W3144644328 cites W2075773303 @default.
• W3144644328 cites W2076079790 @default.
• W3144644328 cites W2076113438 @default.
• W3144644328 cites W2076226743 @default.

• next