Matches in SemOpenAlex for { <https://semopenalex.org/work/W3144741261> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W3144741261 abstract "Rheumatoid arthritis(RA),which is marked by inflammatory synovitis,is a common,chronic autoim-mune-disease,whose pathogenesis is complex and still unclear.In order to explore the effects of heat and hyposmotic stimuli on synoviocytes in rheumatoid arthritis,the changes of [Ca2+]i induced by heat,hyposmotic and 4α-PDD stimuli were observed in synoviocytes.[Ca2+]i elevation induced by heat ≥ 28℃,hyposmotic and 4α-PDD stimuli is found to be positively relative to increasing temperature,decreasing osmolality and rising concentration of 4α-PDD.Results show that there is reciprocity among these stimuli and desensitization,and that [Ca2+]i elevation depends on Ca2+ influx,but not necessarily links to Ca2+ release from intracellular stores and voltage-dependent Ca2+ channel in synoviocytes.The above characteristics of Ca2+ influx are similar to those of TRPV4.A probable mechanism has been suggested that heat and hyposmotic stimulation might increase the level of [Ca2+]i by activating the TRPV4-like channel and Ca2+ influx in the synoviocytes." @default.
- W3144741261 created "2021-04-13" @default.
- W3144741261 creator A5005200123 @default.
- W3144741261 date "2008-01-01" @default.
- W3144741261 modified "2023-09-23" @default.
- W3144741261 title "Heat and hyposmotic stimulation increase in [Ca~(2+)]_i by Ca~(2+) influx in rat synoviocytes" @default.
- W3144741261 hasPublicationYear "2008" @default.
- W3144741261 type Work @default.
- W3144741261 sameAs 3144741261 @default.
- W3144741261 citedByCount "0" @default.
- W3144741261 crossrefType "journal-article" @default.
- W3144741261 hasAuthorship W3144741261A5005200123 @default.
- W3144741261 hasConcept C126322002 @default.
- W3144741261 hasConcept C134018914 @default.
- W3144741261 hasConcept C155164980 @default.
- W3144741261 hasConcept C170493617 @default.
- W3144741261 hasConcept C185592680 @default.
- W3144741261 hasConcept C24998067 @default.
- W3144741261 hasConcept C2780942790 @default.
- W3144741261 hasConcept C55493867 @default.
- W3144741261 hasConcept C71924100 @default.
- W3144741261 hasConcept C79879829 @default.
- W3144741261 hasConcept C90420996 @default.
- W3144741261 hasConceptScore W3144741261C126322002 @default.
- W3144741261 hasConceptScore W3144741261C134018914 @default.
- W3144741261 hasConceptScore W3144741261C155164980 @default.
- W3144741261 hasConceptScore W3144741261C170493617 @default.
- W3144741261 hasConceptScore W3144741261C185592680 @default.
- W3144741261 hasConceptScore W3144741261C24998067 @default.
- W3144741261 hasConceptScore W3144741261C2780942790 @default.
- W3144741261 hasConceptScore W3144741261C55493867 @default.
- W3144741261 hasConceptScore W3144741261C71924100 @default.
- W3144741261 hasConceptScore W3144741261C79879829 @default.
- W3144741261 hasConceptScore W3144741261C90420996 @default.
- W3144741261 hasOpenAccess W3144741261 @default.
- W3144741261 hasRelatedWork W1494209531 @default.
- W3144741261 hasRelatedWork W1967489074 @default.
- W3144741261 hasRelatedWork W1984921570 @default.
- W3144741261 hasRelatedWork W1986933596 @default.
- W3144741261 hasRelatedWork W1987343482 @default.
- W3144741261 hasRelatedWork W2002848696 @default.
- W3144741261 hasRelatedWork W2005277683 @default.
- W3144741261 hasRelatedWork W2015692574 @default.
- W3144741261 hasRelatedWork W2047201618 @default.
- W3144741261 hasRelatedWork W2051609388 @default.
- W3144741261 hasRelatedWork W2060091413 @default.
- W3144741261 hasRelatedWork W2067841245 @default.
- W3144741261 hasRelatedWork W2083229096 @default.
- W3144741261 hasRelatedWork W2133773621 @default.
- W3144741261 hasRelatedWork W2150671779 @default.
- W3144741261 hasRelatedWork W2166501054 @default.
- W3144741261 hasRelatedWork W2347130503 @default.
- W3144741261 hasRelatedWork W2410146512 @default.
- W3144741261 hasRelatedWork W2412787969 @default.
- W3144741261 hasRelatedWork W3140466854 @default.
- W3144741261 isParatext "false" @default.
- W3144741261 isRetracted "false" @default.
- W3144741261 magId "3144741261" @default.
- W3144741261 workType "article" @default.