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- W3144761461 abstract "瞄准：评估 fucoidan 的效果，从海洋的海草的一篇复杂 sulfated 多糖摘录，在丙肝上在 vitro 并且在 vivo 的病毒(HCV ) RNA 负担。方法：HCV-1b 表示 replicon 房间面对从在冲绳栽培的 Cladosiphon okamuranus Tokida 获得的 fucoidan 是有教养的，日本，并且确定 HCV 复制的水平。在开标签的不受管束的研究，有长期的丙肝的 15 个病人，和 HCV 相关的肝硬化和 hepatocellular 癌为 12 瞬间与 fucoidan (0.83 g/d ) 被对待。临床的症状，生物化学的测试，和 HCV RNA 层次以前被估计，在期间，并且在治疗以后。结果：Fucoidan dose-dependently 禁止了 HCV replicon 的表示。在有 fucoidan 的治疗的 8-10 瞬间， HCV RNA 层次相对基线是显著地更低的。一样的治疗也趋于降低浆液丙氨酸 aminotransferase 层次，并且后者与 HCV RNA 层次相关。然而，改进实验室测试没翻译成重要临床的改进。Fucoidan 没有严肃的不利效果。结论：我们的调查结果建议 fucoidan 在有 HCV 相关的长期的肝疾病的病人的治疗安全、有用。进一步控制的临床的试用被需要证实现在的调查结果。" @default.
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- W3144761461 date "2012-01-01" @default.
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- W3144761461 title "Beneficial effects of fucoidan in patients with chronic hepatitis C virus infection" @default.
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