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- W3144884407 abstract "谷胱甘肽 S-transferases (GST ) 戏在 microcystins (MC ) 的 detoxification 的重要角色，而是到 MC-LR 的 GST 的回答很好没在淡水腹足动物被描绘， Cipangopaludina cahayensis。在现在的学习，我们克隆全身的 cDNAs 亩类并且pi班 GST ( GSTM 和 GSTP )和终止类的 GST ( GSTO )的部分 cDNA ，并且决定了三 GST 基因的 transcriptional 回答到 MC-LR 的不同集中( 0 ， 1 ， 10 和 100 ? g/L )在 C 。cahayensis。GSTM 的全身的 cDNAs 和 C 的 GSTP。cahayensis 是 813 和 820 ? bp，包含 648 的一个开的读物框架(ORF )? bp (编码 215 氨基酸) 并且 624 ? bp (编码 207 氨基酸) 分别地。GSTM 和 GSTO 的 mRNA 表示显著地在暴露以后减少了到 10 ? g/L MC-LR，和 GSTP 的 mRNA 表示显著地在 100 以后减少了 ? g/L MC-LR 暴露。这可能在 C 贡献 MC 的解毒。cahayensis，它与它的坐着的生活和过滤喂地位一致。在 C 的三 GST isoforms 的 mRNA 表示。cahayensis 能为水污染被用作 biomarkers。" @default.
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- W3144884407 date "2014-01-01" @default.
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- W3144884407 title "Transcriptional responses of mu-, pi- and omega-class glutathione S-transferase genes in the hepatopancreas of Cipangopaludina cahayensis exposed to microcystin-LR" @default.
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