Matches in SemOpenAlex for { <https://semopenalex.org/work/W3144941201> ?p ?o ?g. }
- W3144941201 endingPage "2170" @default.
- W3144941201 startingPage "2170" @default.
- W3144941201 abstract "Peripheral nerve injuries occur as the result of sudden trauma and lead to reduced quality of life. The peripheral nervous system has an inherent capability to regenerate axons. However, peripheral nerve regeneration following injury is generally slow and incomplete that results in poor functional outcomes such as muscle atrophy. Although conventional surgical procedures for peripheral nerve injuries present many benefits, there are still several limitations including scarring, difficult accessibility to donor nerve, neuroma formation and a need to sacrifice the autologous nerve. For many years, other therapeutic approaches for peripheral nerve injuries have been explored, the most notable being the replacement of Schwann cells, the glial cells responsible for clearing out debris from the site of injury. Introducing cultured Schwann cells to the injured sites showed great benefits in promoting axonal regeneration and functional recovery. However, there are limited sources of Schwann cells for extraction and difficulties in culturing Schwann cells in vitro. Therefore, novel therapeutic avenues that offer maximum benefits for the treatment of peripheral nerve injuries should be investigated. This review focused on strategies using mesenchymal stem cells to promote peripheral nerve regeneration including exosomes of mesenchymal stem cells, nerve engineering using the nerve guidance conduits containing mesenchymal stem cells, and genetically engineered mesenchymal stem cells. We present the current progress of mesenchymal stem cell treatment of peripheral nerve injuries." @default.
- W3144941201 created "2021-04-13" @default.
- W3144941201 creator A5001059474 @default.
- W3144941201 creator A5005354191 @default.
- W3144941201 creator A5019735991 @default.
- W3144941201 creator A5051779733 @default.
- W3144941201 creator A5059199174 @default.
- W3144941201 creator A5059410783 @default.
- W3144941201 creator A5061851245 @default.
- W3144941201 creator A5085136795 @default.
- W3144941201 creator A5086035022 @default.
- W3144941201 date "2021-01-01" @default.
- W3144941201 modified "2023-10-09" @default.
- W3144941201 title "Mesenchymal stem cell treatment for peripheral nerve injury: a narrative review" @default.
- W3144941201 cites W1577776485 @default.
- W3144941201 cites W1586239496 @default.
- W3144941201 cites W1601173130 @default.
- W3144941201 cites W1842503083 @default.
- W3144941201 cites W1938236935 @default.
- W3144941201 cites W1964585328 @default.
- W3144941201 cites W1967229101 @default.
- W3144941201 cites W1969821478 @default.
- W3144941201 cites W1974574277 @default.
- W3144941201 cites W1984781427 @default.
- W3144941201 cites W1989516473 @default.
- W3144941201 cites W2006416266 @default.
- W3144941201 cites W2009434374 @default.
- W3144941201 cites W2015121221 @default.
- W3144941201 cites W2035551042 @default.
- W3144941201 cites W2038882277 @default.
- W3144941201 cites W2049099403 @default.
- W3144941201 cites W2050424280 @default.
- W3144941201 cites W2057315313 @default.
- W3144941201 cites W2064317688 @default.
- W3144941201 cites W2066234893 @default.
- W3144941201 cites W2073267177 @default.
- W3144941201 cites W2080602624 @default.
- W3144941201 cites W2085088947 @default.
- W3144941201 cites W2091994305 @default.
- W3144941201 cites W2098751075 @default.
- W3144941201 cites W2099369804 @default.
- W3144941201 cites W2100704394 @default.
- W3144941201 cites W2107826905 @default.
- W3144941201 cites W2109298880 @default.
- W3144941201 cites W2113460739 @default.
- W3144941201 cites W2118145481 @default.
- W3144941201 cites W2120002445 @default.
- W3144941201 cites W2134307023 @default.
- W3144941201 cites W2135032585 @default.
- W3144941201 cites W2140306359 @default.
- W3144941201 cites W2154741341 @default.
- W3144941201 cites W2166550152 @default.
- W3144941201 cites W2168120562 @default.
- W3144941201 cites W2172103539 @default.
- W3144941201 cites W2173497140 @default.
- W3144941201 cites W2221267861 @default.
- W3144941201 cites W2264863733 @default.
- W3144941201 cites W2265559997 @default.
- W3144941201 cites W2273521760 @default.
- W3144941201 cites W2278098644 @default.
- W3144941201 cites W2301107184 @default.
- W3144941201 cites W2403101800 @default.
- W3144941201 cites W2418913553 @default.
- W3144941201 cites W2515556545 @default.
- W3144941201 cites W2517879681 @default.
- W3144941201 cites W2559871461 @default.
- W3144941201 cites W2560194931 @default.
- W3144941201 cites W2564115845 @default.
- W3144941201 cites W2581219109 @default.
- W3144941201 cites W2596438720 @default.
- W3144941201 cites W2597520820 @default.
- W3144941201 cites W2605484523 @default.
- W3144941201 cites W2624253730 @default.
- W3144941201 cites W2735775614 @default.
- W3144941201 cites W2746492067 @default.
- W3144941201 cites W2749338501 @default.
- W3144941201 cites W2758616494 @default.
- W3144941201 cites W2770328981 @default.
- W3144941201 cites W2785643516 @default.
- W3144941201 cites W2791293843 @default.
- W3144941201 cites W2791419606 @default.
- W3144941201 cites W2801025021 @default.
- W3144941201 cites W2807768865 @default.
- W3144941201 cites W2808993958 @default.
- W3144941201 cites W2889146606 @default.
- W3144941201 cites W2889433138 @default.
- W3144941201 cites W2890854352 @default.
- W3144941201 cites W2891936075 @default.
- W3144941201 cites W2898011915 @default.
- W3144941201 cites W2898945039 @default.
- W3144941201 cites W2900532562 @default.
- W3144941201 cites W2902983462 @default.
- W3144941201 cites W2912343418 @default.
- W3144941201 cites W2914525518 @default.
- W3144941201 cites W2926530156 @default.
- W3144941201 cites W2937071030 @default.
- W3144941201 cites W2970026792 @default.
- W3144941201 cites W2972327304 @default.