Matches in SemOpenAlex for { <https://semopenalex.org/work/W3144984926> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W3144984926 endingPage "248" @default.
- W3144984926 startingPage "240" @default.
- W3144984926 abstract "间充质的干细胞(MSC ) ，源于成年纸巾，是 multipotentprogenitor 房间，它为再生药保持大诺言。最近的研究证明了 thatMSCs 在动物和人是抑制免疫力的体内和试管内。然而，管理 MSC 的这些有免疫力的调节功能的机制留下大部分逃犯。有 MSC 的体积人口的一些研究显示象 PGE2 和 TGFbeta 那样的可溶的因素是重要的，当其它为房间房间接触支持一个角色时。在这研究，我们打算由检验克隆的 MSC 的抑制免疫力的效果澄清这些问题。我们从老鼠骨髓导出 MSC 克隆并且证明这些克隆的多数能区分进 adipocytes 象 andosteoblast 一样房间。重要地，从这些克隆的房间展出了强壮的禁止的效果 onTCR 这些房间的一个小数字的导致激活的 T 细胞增殖试管内，和注射在老鼠支持了 allogeneic 皮肤接枝的幸存。从 MSC 文化的调节媒介证明 anti-CD3 上的某禁止的效果导致了独立于 PGE2 andTGFbeta 的淋巴细胞增长。在比较，有刺激淋巴细胞的 MSC 的直接合作文化导致了许多更强壮的抑制免疫力的效果。有趣地，抑制是双向的，当 MSCproliferation 也面对淋巴细胞被减少。一起拿，我们有克隆的 MSC 的调查结果证明这些房间通过可溶的因素和房间房间施加他们的抑制免疫力的效果接触，和那淋巴细胞和 MSC 在他们的各自的增长上是互相禁止的。" @default.
- W3144984926 created "2021-04-13" @default.
- W3144984926 creator A5001870409 @default.
- W3144984926 creator A5001978013 @default.
- W3144984926 creator A5007338324 @default.
- W3144984926 creator A5007429737 @default.
- W3144984926 creator A5010669990 @default.
- W3144984926 creator A5012233047 @default.
- W3144984926 creator A5022476919 @default.
- W3144984926 creator A5022768794 @default.
- W3144984926 creator A5031574504 @default.
- W3144984926 creator A5032483419 @default.
- W3144984926 creator A5047935895 @default.
- W3144984926 creator A5052925986 @default.
- W3144984926 creator A5065175416 @default.
- W3144984926 date "2007-01-01" @default.
- W3144984926 modified "2023-09-24" @default.
- W3144984926 title "Immunosuppressive properties of cloned bone marrow mesenchymal stem cells" @default.
- W3144984926 hasPublicationYear "2007" @default.
- W3144984926 type Work @default.
- W3144984926 sameAs 3144984926 @default.
- W3144984926 citedByCount "0" @default.
- W3144984926 crossrefType "journal-article" @default.
- W3144984926 hasAuthorship W3144984926A5001870409 @default.
- W3144984926 hasAuthorship W3144984926A5001978013 @default.
- W3144984926 hasAuthorship W3144984926A5007338324 @default.
- W3144984926 hasAuthorship W3144984926A5007429737 @default.
- W3144984926 hasAuthorship W3144984926A5010669990 @default.
- W3144984926 hasAuthorship W3144984926A5012233047 @default.
- W3144984926 hasAuthorship W3144984926A5022476919 @default.
- W3144984926 hasAuthorship W3144984926A5022768794 @default.
- W3144984926 hasAuthorship W3144984926A5031574504 @default.
- W3144984926 hasAuthorship W3144984926A5032483419 @default.
- W3144984926 hasAuthorship W3144984926A5047935895 @default.
- W3144984926 hasAuthorship W3144984926A5052925986 @default.
- W3144984926 hasAuthorship W3144984926A5065175416 @default.
- W3144984926 hasConcept C198826908 @default.
- W3144984926 hasConcept C203014093 @default.
- W3144984926 hasConcept C2780007613 @default.
- W3144984926 hasConcept C86803240 @default.
- W3144984926 hasConcept C95444343 @default.
- W3144984926 hasConceptScore W3144984926C198826908 @default.
- W3144984926 hasConceptScore W3144984926C203014093 @default.
- W3144984926 hasConceptScore W3144984926C2780007613 @default.
- W3144984926 hasConceptScore W3144984926C86803240 @default.
- W3144984926 hasConceptScore W3144984926C95444343 @default.
- W3144984926 hasIssue "3" @default.
- W3144984926 hasLocation W31449849261 @default.
- W3144984926 hasOpenAccess W3144984926 @default.
- W3144984926 hasPrimaryLocation W31449849261 @default.
- W3144984926 hasRelatedWork W2212544296 @default.
- W3144984926 hasRelatedWork W2278084328 @default.
- W3144984926 hasRelatedWork W2415285546 @default.
- W3144984926 hasRelatedWork W2437514510 @default.
- W3144984926 hasRelatedWork W2991026960 @default.
- W3144984926 hasRelatedWork W2998705336 @default.
- W3144984926 hasRelatedWork W3000263994 @default.
- W3144984926 hasRelatedWork W3044204620 @default.
- W3144984926 hasRelatedWork W3140559653 @default.
- W3144984926 hasRelatedWork W3142490774 @default.
- W3144984926 hasRelatedWork W3144082226 @default.
- W3144984926 hasRelatedWork W3145897588 @default.
- W3144984926 hasRelatedWork W3146585015 @default.
- W3144984926 hasRelatedWork W3147099513 @default.
- W3144984926 hasRelatedWork W3148154825 @default.
- W3144984926 hasRelatedWork W3148281546 @default.
- W3144984926 hasRelatedWork W3149309739 @default.
- W3144984926 hasRelatedWork W3149482830 @default.
- W3144984926 hasRelatedWork W3150315939 @default.
- W3144984926 hasRelatedWork W3150729398 @default.
- W3144984926 hasVolume "17" @default.
- W3144984926 isParatext "false" @default.
- W3144984926 isRetracted "false" @default.
- W3144984926 magId "3144984926" @default.
- W3144984926 workType "article" @default.