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• W3145267238 abstract "Back to table of contents Next article No AccessNeuroleptic malignant syndromePublished Online:1 Apr 2006https://doi.org/10.1176/ajp.142.10.1137AboutSectionsView articleAbstractPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail View articleAbstractNeuroleptic malignant syndrome is a rare but serious adverse effect of antipsychotic medication. The author describes three new cases and reviews 50 others published in the past 5 years. Demographic and clinical features, diagnosis, treatment, outcome, and pathophysiology are critically reviewed, and a new set of diagnostic criteria, incorporating physical signs and routine laboratory tests, is proposed. Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). 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DICP, Vol. 24, No. 7-8Risk Management for Extrapyramidal SymptomsQRB - Quality Review Bulletin, Vol. 16, No. 3Combined Use of Haloperidol and LithiumPsychiatric Annals, Vol. 20, No. 3Biological Psychiatry, Vol. 27, No. 3Biological Psychiatry, Vol. 28, No. 6Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 14, No. 1General Pharmacology: The Vascular System, Vol. 21, No. 4, Vol. 14Clinical Oncology, Vol. 2, No. 4Irish Journal of Psychological Medicine, Vol. 7, No. 2Acta Psychiatrica Scandinavica, Vol. 82, No. 3Acta Psychiatrica Scandinavica, Vol. 81, No. 1Acta Psychiatrica Scandinavica, Vol. 81, No. 2Journal of Neurology, Neurosurgery & Psychiatry, Vol. 53, No. 6British Journal of Psychiatry, Vol. 157, No. 3Nordisk Psykiatrisk Tidsskrift, Vol. 44, No. 1Verifying Patients' Reports of Childhood AbuseCHARLES L. RICH1 April 2006 | American Journal of Psychiatry, Vol. 146, No. 10Drs. Burket and Hodgin ReplyROGER C. BURKET, and JON D. HODGIN1 April 2006 | American Journal of Psychiatry, Vol. 146, No. 10Derealization Without DepersonalizationGEORGE O. KRIZEK1 April 2006 | American Journal of Psychiatry, Vol. 146, No. 10Verifying patients' reports of childhood abuse23 January 2015 | American Journal of Psychiatry, Vol. 146, No. 10Neuroleptic Malignant Syndrome in a Child Treated With Metoclopramide for Chemotherapy-Related Nausea2 July 2016 | Journal of Child Neurology, Vol. 4, No. 3Neuroleptic Malignant Syndrome: Recognizing an Unrecognized KillerJournal of Psychosocial Nursing and Mental Health Services, Vol. 27, No. 7A prospective analysis of 24 episodes of neuroleptic malignant syndrome1 April 2006 | American Journal of Psychiatry, Vol. 146, No. 6Use of Neuroleptics after an Episode of Neuroleptic Malignant Syndrome1 May 1989 | The Canadian Journal of Psychiatry, Vol. 34, No. 4Neuroleptic malignant syndrome and compulsive drinking of water1 April 1989 | Medical Journal of Australia, Vol. 150, No. 8Clinical differentiation between lethal catatonia and neuroleptic malignant syndrome1 April 2006 | American Journal of Psychiatry, Vol. 146, No. 3Dangerously aggressive behavior as a side effect of alprazolam1 April 2006 | American Journal of Psychiatry, Vol. 146, No. 2Delirium in runners1 April 2006 | American Journal of Psychiatry, Vol. 146, No. 2, Vol. 1Cell Calcium, Vol. 10, No. 4General Hospital Psychiatry, Vol. 11, No. 4Annals of Emergency Medicine, Vol. 18, No. 10Acta Anaesthesiologica Scandinavica, Vol. 33, No. 8Journal of Neurology, Neurosurgery & Psychiatry, Vol. 52, No. 8Amoxapine-Induced Neuroleptic Malignant Syndrome30 May 2017 | DICP, Vol. 23, No. 1British Journal of Psychiatry, Vol. 155, No. 1British Journal of Psychiatry, Vol. 155, No. 4British Journal of Psychiatry, Vol. 155, No. 6Nordisk Psykiatrisk Tidsskrift, Vol. 43, No. 5Die Stellung katatoner Syndrome zwischen den affektiven und schizophrenen PsychosenRisk of malignant hyperthermia among patients with neuroleptic malignant syndrome and their families1 April 2006 | American Journal of Psychiatry, Vol. 145, No. 11Neuroleptic Malignant Syndrome Treated with Diazepam1 November 1988 | The Canadian Journal of Psychiatry, Vol. 33, No. 8Combined drug therapy for an elderly depressed patient1 April 2006 | American Journal of Psychiatry, Vol. 145, No. 8Tolerance of a high dose of haloperidol by an elderly patient1 April 2006 | American Journal of Psychiatry, Vol. 145, No. 8Neuroleptic Rechallenge after Neuroleptic Malignant Syndrome: Case Report and Literature Review5 December 2017 | Drug Intelligence & Clinical Pharmacy, Vol. 22, No. 6Hypothalamic pathology in the neuroleptic malignant syndrome1 April 2006 | American Journal of Psychiatry, Vol. 145, No. 5Haloperidol in neuroleptic malignant syndrome1 April 2006 | American Journal of Psychiatry, Vol. 145, No. 5Dr. Keck and Associates ReplyPAUL E. KECKJR., HARRISON G. POPEJR., and SUSAN L. MCELROY1 April 2006 | American Journal of Psychiatry, Vol. 145, No. 5Too Many Psychiatrists?MARVIN H. LIPKOWITZ1 April 2006 | American Journal of Psychiatry, Vol. 145, No. 5Too many psychiatrists?23 January 2015 | American Journal of Psychiatry, Vol. 145, No. 5Pharmacoepidemiology Methods for Identifying and Quantifying Behavioral Effects of Neuropharmacological Agents30 May 2017 | Drug Intelligence & Clinical Pharmacy, Vol. 22, No. 3The role of external heat load in triggering the neuroleptic malignant syndrome1 April 2006 | American Journal of Psychiatry, Vol. 145, No. 1Journal of Neurology, Vol. 235, No. 5Irish Journal of Medical Science, Vol. 157, No. 10Biological Psychiatry, Vol. 24, No. 8The American Journal of Medicine, Vol. 85, No. 6Psychosomatics, Vol. 29, No. 2Psychosomatics, Vol. 29, No. 1The Lancet, Vol. 332, No. 8626-8627Neuroscience & Biobehavioral Reviews, Vol. 12, No. 3-4Clinics in Geriatric Medicine, Vol. 4, No. 4British Journal of Psychiatry, Vol. 152, No. 4British Journal of Psychiatry, Vol. 152, No. 4British Journal of Psychiatry, Vol. 153, No. 1The American Journal of Drug and Alcohol Abuse, Vol. 14, No. 3Annals of Saudi Medicine, Vol. 8, No. 2Dr. Lazarus and Associates ReplyLAWRENCE W. LAZARUS, NANCY NEWTON, BERTRAM COHLER, JARY LESSER, and CRAIG SCHWEON1 April 2006 | American Journal of Psychiatry, Vol. 144, No. 10Diagnosing and Defining Neuroleptic Malignant Syndrome ADITYANJEE1 April 2006 | American Journal of Psychiatry, Vol. 144, No. 10Utilization of Mental Health Care ServicesDILIP RAMCHANDANI1 April 2006 | American Journal of Psychiatry, Vol. 144, No. 10Neuroleptic malignant syndrome and lethal catatonia23 January 2015 | American Journal of Psychiatry, Vol. 144, No. 10Psychotic reaction to an insect repellent1 April 2006 | American Journal of Psychiatry, Vol. 144, No. 8Neuroleptic Malignant Syndrome: Facts and Controversies ADITYANJEE1 April 2006 | American Journal of Psychiatry, Vol. 144, No. 8Dr. Sternberg RepliesDAVID E. STERNBERG1 April 2006 | American Journal of Psychiatry, Vol. 144, No. 8Symptoms of Neuroleptic Malignant SyndromeJOSEPH H. FRIEDMAN, and RICHARD L. WAGNER1 April 2006 | American Journal of Psychiatry, Vol. 144, No. 8Dr. Addonizio and Colleagues ReplyGERARD ADDONIZIO, VIRGINIA L. SUSMAN, and STEVEN D. ROTH1 April 2006 | American Journal of Psychiatry, Vol. 144, No. 8Neuroleptic malignant syndrome: facts and controversies23 January 2015 | American Journal of Psychiatry, Vol. 144, No. 8Symptoms of neuroleptic malignant syndrome23 January 2015 | American Journal of Psychiatry, Vol. 144, No. 8The Neuroleptic Malignant Syndrome: A Clinical UpdatePsychiatric Annals, Vol. 17, No. 8Dr. Garbutt and Associates ReplyJAMES C. GARBUTT, JAMES P. MAYO, and GREGORY M. GILLETTE1 April 2006 | American Journal of Psychiatry, Vol. 144, No. 4Mortality in Neuroleptic Malignant SyndromeADITYAN JEE1 April 2006 | American Journal of Psychiatry, Vol. 144, No. 4The Soviet View of Paranoid DisorderLESLIE SOLYOM1 April 2006 | American Journal of Psychiatry, Vol. 144, No. 4The Soviet view of paranoid disorder23 January 2015 | American Journal of Psychiatry, Vol. 144, No. 4, Vol. 5Canadian Journal of Anaesthesia, Vol. 34, No. 5Biological Psychiatry, Vol. 22, No. 8General Hospital Psychiatry, Vol. 9, No. 3The Lancet, Vol. 329, No. 8543, Vol. 11Frequency of the Neuroleptic Malignant Syndrome, 1963-198628 April 2020 | Psychiatry and Psychobiology, Vol. 2, No. 1The Journal of General Psychology, Vol. 114, No. 1Postgraduate Medicine, Vol. 81, No. 5Journal of the American Geriatrics Society, Vol. 35, No. 11Acta Neurologica Scandinavica, Vol. 75, No. 3Acta Neurologica Scandinavica, Vol. 75, No. 3Acta Psychiatrica Scandinavica, Vol. 75, No. 3Journal of Neurology, Neurosurgery & Psychiatry, Vol. 50, No. 4Journal of Neurology, Neurosurgery & Psychiatry, Vol. 50, No. 4Journal of Neurology, Neurosurgery & Psychiatry, Vol. 50, No. 4Lethal catatonia1 April 2006 | American Journal of Psychiatry, Vol. 143, No. 11NEUROLEPTIC MALIGNANT SYNDROMEJournal of Psychosocial Nursing and Mental Health Services, Vol. 24, No. 9The adverse effects of intensive treatment of chronic schizophreniaComprehensive Psychiatry, Vol. 27, No. 4Annals of Emergency Medicine, Vol. 15, No. 8Postgraduate Medicine, Vol. 80, No. 3 Volume 142Issue 10 October 1985Pages 1137-1145 Metrics PDF download History Published online 1 April 2006 Published in print 1 October 1985" @default.
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