Matches in SemOpenAlex for { <https://semopenalex.org/work/W3145366352> ?p ?o ?g. }
- W3145366352 abstract "Abstract Most techniques allow detection of protein unfolding either by following the behaviour of single reporters or as an averaged all-or-none process. We recently added 2D NMR spectroscopy to the well-established techniques able to obtain information on the process of unfolding using resonances of residues in the hydrophobic core of a protein. Here, we questioned whether an analysis of the individual stability curves from each resonance could provide additional site-specific information. We used the Yfh1 protein that has the unique feature to undergo both cold and heat denaturation at temperatures above water freezing at low ionic strength. We show that stability curves inconsistent with the average NMR curve from hydrophobic core residues mainly comprise exposed outliers that do nevertheless provide precious information. By monitoring both cold and heat denaturation of individual residues we gain knowledge on the process of cold denaturation and convincingly demonstrate that the two unfolding processes are intrinsically different." @default.
- W3145366352 created "2021-04-13" @default.
- W3145366352 creator A5003139041 @default.
- W3145366352 creator A5008081293 @default.
- W3145366352 creator A5039746487 @default.
- W3145366352 creator A5044977074 @default.
- W3145366352 creator A5090092430 @default.
- W3145366352 date "2021-03-29" @default.
- W3145366352 modified "2023-09-27" @default.
- W3145366352 title "Anatomy of unfolding: The site-specific fold stability of Yfh1 measured by 2D NMR" @default.
- W3145366352 cites W1891587661 @default.
- W3145366352 cites W1968998311 @default.
- W3145366352 cites W1969620541 @default.
- W3145366352 cites W1972459558 @default.
- W3145366352 cites W1982481819 @default.
- W3145366352 cites W1992019748 @default.
- W3145366352 cites W1994587961 @default.
- W3145366352 cites W2007074187 @default.
- W3145366352 cites W2008708467 @default.
- W3145366352 cites W2008818819 @default.
- W3145366352 cites W2017187908 @default.
- W3145366352 cites W2020476383 @default.
- W3145366352 cites W2021736649 @default.
- W3145366352 cites W2035338880 @default.
- W3145366352 cites W2040650484 @default.
- W3145366352 cites W2053717316 @default.
- W3145366352 cites W2057246411 @default.
- W3145366352 cites W2058900218 @default.
- W3145366352 cites W2060875398 @default.
- W3145366352 cites W2062332413 @default.
- W3145366352 cites W2062535863 @default.
- W3145366352 cites W2069879098 @default.
- W3145366352 cites W2075075608 @default.
- W3145366352 cites W2078933151 @default.
- W3145366352 cites W2101328551 @default.
- W3145366352 cites W2110740104 @default.
- W3145366352 cites W2123254545 @default.
- W3145366352 cites W2128716813 @default.
- W3145366352 cites W2132727000 @default.
- W3145366352 cites W2139327615 @default.
- W3145366352 cites W2141179031 @default.
- W3145366352 cites W2152375064 @default.
- W3145366352 cites W2157006014 @default.
- W3145366352 cites W2171190723 @default.
- W3145366352 cites W2238207809 @default.
- W3145366352 cites W2256578114 @default.
- W3145366352 cites W2547161617 @default.
- W3145366352 cites W2591903820 @default.
- W3145366352 cites W2606511255 @default.
- W3145366352 cites W2614314148 @default.
- W3145366352 cites W2788339511 @default.
- W3145366352 cites W2793363633 @default.
- W3145366352 cites W3022255598 @default.
- W3145366352 cites W3048016986 @default.
- W3145366352 doi "https://doi.org/10.1101/2021.03.27.437329" @default.
- W3145366352 hasPublicationYear "2021" @default.
- W3145366352 type Work @default.
- W3145366352 sameAs 3145366352 @default.
- W3145366352 citedByCount "0" @default.
- W3145366352 crossrefType "posted-content" @default.
- W3145366352 hasAuthorship W3145366352A5003139041 @default.
- W3145366352 hasAuthorship W3145366352A5008081293 @default.
- W3145366352 hasAuthorship W3145366352A5039746487 @default.
- W3145366352 hasAuthorship W3145366352A5044977074 @default.
- W3145366352 hasAuthorship W3145366352A5090092430 @default.
- W3145366352 hasBestOaLocation W31453663521 @default.
- W3145366352 hasConcept C12554922 @default.
- W3145366352 hasConcept C13965031 @default.
- W3145366352 hasConcept C159467904 @default.
- W3145366352 hasConcept C185592680 @default.
- W3145366352 hasConcept C204328495 @default.
- W3145366352 hasConcept C2776923230 @default.
- W3145366352 hasConcept C2988375501 @default.
- W3145366352 hasConcept C55493867 @default.
- W3145366352 hasConcept C66974803 @default.
- W3145366352 hasConcept C71240020 @default.
- W3145366352 hasConcept C8010536 @default.
- W3145366352 hasConcept C86803240 @default.
- W3145366352 hasConceptScore W3145366352C12554922 @default.
- W3145366352 hasConceptScore W3145366352C13965031 @default.
- W3145366352 hasConceptScore W3145366352C159467904 @default.
- W3145366352 hasConceptScore W3145366352C185592680 @default.
- W3145366352 hasConceptScore W3145366352C204328495 @default.
- W3145366352 hasConceptScore W3145366352C2776923230 @default.
- W3145366352 hasConceptScore W3145366352C2988375501 @default.
- W3145366352 hasConceptScore W3145366352C55493867 @default.
- W3145366352 hasConceptScore W3145366352C66974803 @default.
- W3145366352 hasConceptScore W3145366352C71240020 @default.
- W3145366352 hasConceptScore W3145366352C8010536 @default.
- W3145366352 hasConceptScore W3145366352C86803240 @default.
- W3145366352 hasLocation W31453663521 @default.
- W3145366352 hasLocation W31453663522 @default.
- W3145366352 hasOpenAccess W3145366352 @default.
- W3145366352 hasPrimaryLocation W31453663521 @default.
- W3145366352 hasRelatedWork W1858709370 @default.
- W3145366352 hasRelatedWork W2004644004 @default.
- W3145366352 hasRelatedWork W2008935619 @default.
- W3145366352 hasRelatedWork W2016081971 @default.
- W3145366352 hasRelatedWork W2070504654 @default.
- W3145366352 hasRelatedWork W2161429104 @default.