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- W3145429642 abstract "The comparative morphohistochemical study of the sciatic nerve was performed in rats by the method of detecting Ca2+-dependent acid phosphatase activity at different periods after the crush. It was shown that in 2 hours the activity abruptly decreased at the site of injury, but in 5 days there was a recovery from the proximal area, although a tendency to degeneration of the nerve distal segment was outlined. Moderate proliferation of Schwann cells and endoneurium cells were observed since day 13 after crush; in 35 days the restoration of enzyme activity only in the extensor bundles of fibers (n. peroneus communis) was registered. In 70 days after Schwann cells crushing, a connective tissue layer between the nerve fibre bundles and cross-collaterals of nerve fibre winding the adjacent muscles was detected. To confirm the results of morphohistochemical study, the electrophysiological investigation was carried out to record the spinal cord single motoneurons activity to stimulation of extensor and flexor (n. gastrocnemius) branches of Schwann cells. Software analysis revealed a progressive increase of excitatory poststimulus reactions not reaching the normal level for flexor in contrast to the extensor nerve. Depressor effects, almost twice exceeding the normal levels and more pronounced for the extensor nerve, suggest the possible impact of the protective purpose. The use of pharmacological protection in order to accelerate the rehabilitation of the damaged nerve might be required." @default.
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- W3145429642 date "2011-01-01" @default.
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- W3145429642 title "ELECTROPHYSIOLOGICAL AND MORPHOHISTOCHEMICAL STUDY ON DYNAMICS OF DEGENERATIVE AND REGENERATIVE PROCESSES IN FLEXOR AND EXTENSOR BRANCHES OF SCIATIC NERVE AFTER THE CRUSH" @default.
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