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- W3145454815 abstract "调查三氧化二砷(As2O3 ) 的颠倒效果在上的目的多，人的胃的肿瘤 SGC7901/ADR 房间的药抵抗排队到 adriamycin (ADM ) 和它的颠倒机制。As2O3 的非细胞毒素的集中和到 ADM 的 SGC7901/ADR 房间的敏感被 MTT 试金检测的方法。药集中和 SGC7901/ADR 房间的 P-gp 功能与流动被测量血细胞计数(FCM ) ，和 GST- π和 SGC7901/ADR 房间的 Topo II 表达式上的 As2O3 的影响被免疫分析组织化学的方法。在 0.4 ～ 0.8 μ m ol/L 集中的结果 As2O3 不对 SGC7901/ADR 房间显著地细胞毒素。在 0.8 μ m ol/L 的 As2O3 能经由禁止 P-gp 功能改进 SGC7901/ADR 房间的敏感到 ADM，下面调整的 GST- π表示并且在 SGC7901/ADR 房间增加 ADM 的细胞内部的累积。结论 As2O3 能部分颠倒 SGC7901/ADR 房间的药抵抗到 ADM，它可能与禁止 P-gp 函数和下面调整的 GST- π表示是相关的。" @default.
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- W3145454815 date "2007-01-01" @default.
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- W3145454815 title "Reversal mechanism of arsenic trioxide in the drug resistance of human gastric cancer cell line SGC7901/ADR" @default.
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