Matches in SemOpenAlex for { <https://semopenalex.org/work/W3145703691> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W3145703691 endingPage "121" @default.
- W3145703691 startingPage "115" @default.
- W3145703691 abstract "non-overexpression ErbB2 乳癌房间 MDA-MB-231 的目的将在 ErbB2 受体信号 transduction 小径激活上探索 neuregulins 的效果，和侵略和转移。neuregulin 的表情被免疫细胞化学和西方的污点检测的方法。MDA-MB-231 房间与 ErbB2 kinase 禁止者 AG825 被对待。增长与 MTT 试金被测量。MDA-ME-231 房间的侵略和转移与 transwell 房间被评估。MMP-2 和 MMP-9 的酶活动被明胶 zymography 检测。MMP-2 和 HIF-1α 的表情被西方的污点检测。结果 MDA-MB-231 房间表示了一 neuregulin 相对高级。在西方的污点，积极反应乐队在与 NRG 的分子的重量与一致的 44KD 被发现。当 MDA-MB-231 房间与 AG825 被对待时，增长在 time-dose-dependent 被禁止举止(P<0.01 ) ，侵略和转移也被压抑(P<0.05 ) 。MMP-2 和 MMP-9 的酶活动更低(P<0.05 ) 。MMP-2 和 HIF-1α 的表示层次被减少(P<0.05 ) 。我们的学习显示那 neuregulins 的结论作为 transmembrane 蛋白质在 MDA-MB-231 房间被综合， neuregulins 能由 autocrine 或 paracrine 分泌物激活 ErbB2 受体信号 transduction 小径，并且导致 MDA-MB-231 房间的侵略和转移。" @default.
- W3145703691 created "2021-04-13" @default.
- W3145703691 creator A5001978013 @default.
- W3145703691 creator A5002591266 @default.
- W3145703691 creator A5014979964 @default.
- W3145703691 creator A5032483419 @default.
- W3145703691 creator A5038372228 @default.
- W3145703691 creator A5060967773 @default.
- W3145703691 date "2009-01-01" @default.
- W3145703691 modified "2023-09-24" @default.
- W3145703691 title "Effects of Neuregulins on Invasion and Metastasis of Non-overexpression ErbB2 Breast Cancer Cells" @default.
- W3145703691 hasPublicationYear "2009" @default.
- W3145703691 type Work @default.
- W3145703691 sameAs 3145703691 @default.
- W3145703691 citedByCount "0" @default.
- W3145703691 crossrefType "journal-article" @default.
- W3145703691 hasAuthorship W3145703691A5001978013 @default.
- W3145703691 hasAuthorship W3145703691A5002591266 @default.
- W3145703691 hasAuthorship W3145703691A5014979964 @default.
- W3145703691 hasAuthorship W3145703691A5032483419 @default.
- W3145703691 hasAuthorship W3145703691A5038372228 @default.
- W3145703691 hasAuthorship W3145703691A5060967773 @default.
- W3145703691 hasConcept C109523444 @default.
- W3145703691 hasConcept C126322002 @default.
- W3145703691 hasConcept C128240485 @default.
- W3145703691 hasConcept C134018914 @default.
- W3145703691 hasConcept C170493617 @default.
- W3145703691 hasConcept C177430391 @default.
- W3145703691 hasConcept C185323287 @default.
- W3145703691 hasConcept C185592680 @default.
- W3145703691 hasConcept C2778560701 @default.
- W3145703691 hasConcept C502942594 @default.
- W3145703691 hasConcept C62478195 @default.
- W3145703691 hasConcept C71924100 @default.
- W3145703691 hasConcept C7876069 @default.
- W3145703691 hasConcept C86803240 @default.
- W3145703691 hasConcept C95444343 @default.
- W3145703691 hasConceptScore W3145703691C109523444 @default.
- W3145703691 hasConceptScore W3145703691C126322002 @default.
- W3145703691 hasConceptScore W3145703691C128240485 @default.
- W3145703691 hasConceptScore W3145703691C134018914 @default.
- W3145703691 hasConceptScore W3145703691C170493617 @default.
- W3145703691 hasConceptScore W3145703691C177430391 @default.
- W3145703691 hasConceptScore W3145703691C185323287 @default.
- W3145703691 hasConceptScore W3145703691C185592680 @default.
- W3145703691 hasConceptScore W3145703691C2778560701 @default.
- W3145703691 hasConceptScore W3145703691C502942594 @default.
- W3145703691 hasConceptScore W3145703691C62478195 @default.
- W3145703691 hasConceptScore W3145703691C71924100 @default.
- W3145703691 hasConceptScore W3145703691C7876069 @default.
- W3145703691 hasConceptScore W3145703691C86803240 @default.
- W3145703691 hasConceptScore W3145703691C95444343 @default.
- W3145703691 hasIssue "2" @default.
- W3145703691 hasLocation W31457036911 @default.
- W3145703691 hasOpenAccess W3145703691 @default.
- W3145703691 hasPrimaryLocation W31457036911 @default.
- W3145703691 hasRelatedWork W1970679909 @default.
- W3145703691 hasRelatedWork W1976340620 @default.
- W3145703691 hasRelatedWork W1978919038 @default.
- W3145703691 hasRelatedWork W2008913484 @default.
- W3145703691 hasRelatedWork W2038009082 @default.
- W3145703691 hasRelatedWork W2049800885 @default.
- W3145703691 hasRelatedWork W2161975859 @default.
- W3145703691 hasRelatedWork W2238627408 @default.
- W3145703691 hasRelatedWork W2261120022 @default.
- W3145703691 hasRelatedWork W2313466771 @default.
- W3145703691 hasRelatedWork W2332808705 @default.
- W3145703691 hasRelatedWork W2410352801 @default.
- W3145703691 hasRelatedWork W2583912087 @default.
- W3145703691 hasRelatedWork W2740856811 @default.
- W3145703691 hasRelatedWork W2760328201 @default.
- W3145703691 hasRelatedWork W2949000019 @default.
- W3145703691 hasRelatedWork W2988927692 @default.
- W3145703691 hasRelatedWork W3150094081 @default.
- W3145703691 hasRelatedWork W3150109602 @default.
- W3145703691 hasRelatedWork W3177717726 @default.
- W3145703691 hasVolume "21" @default.
- W3145703691 isParatext "false" @default.
- W3145703691 isRetracted "false" @default.
- W3145703691 magId "3145703691" @default.
- W3145703691 workType "article" @default.