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- W3145816096 abstract "Objective To assess the value of near-infrared spectroscopy (NIRS) on monitoring cerebral oxygenation during different cardiopulmonary bypass(CPB). Methods Twenty-four patients with ventricular septal defect combined with pulmonary hypertension undergoing open heart operation were randomly assigned to 3 groups: moderate hypothermia cardiopulmonary bypass(MHCPB) group(n=6), deep hypothermia low flow(DHLF) group (n=6)and deep hypothermia circulatory arrest(DHCA) group (n=12). NIRS data including cerebral oxygenated hemoglobin (HbO 2) , deoxygenated hemoglobin(HbD), oxidized cytochrome aa 3(CytOx) and oxygenated hemoglobin signal nadir time(HbO 2-NT) were tested, lactate (Lact) and neuron-specific enolase (NSE), electroencephalography(EEG) were measured, and correlation analysis of all these data were undertaken. Results NIRS data showed no correlation with biochemical data and EEG in MHCPB group and DHLF group; the minimum value of HbO 2 , CytOx and HbO 2-NT were closely correlated with increase in Lact and NSE. All patients in which HbO 2-NT less than 35 minutes were free of behavioral evidence of brain injury. Conclusions NIRS data including the minimum value of HbO 2, CytOx and HbO 2-NT showed strong correlation with other cerebral function assessment during DHCA, HbO 2-NT determined by NIRS monitoring is a useful predictor of safe duration of circulatory arrest." @default.
- W3145816096 created "2021-04-13" @default.
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- W3145816096 date "2003-01-01" @default.
- W3145816096 modified "2023-09-27" @default.
- W3145816096 title "Monitoring of cerebral oxygenation by near-infrared spectroscopy during cardiopulmonary bypass in infants" @default.
- W3145816096 hasPublicationYear "2003" @default.
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