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- W3145932009 abstract "Hos3 is involved in cellular growth under osmotic stress in Schizosaccharomyces pombe. The recom- binant plasmid pYFHos3 harboring the structural gene encoding Hos3 was constructed. The S. pombe cells har- boring pYFHos3 contained the increased hos3 ? mRNA content and exhibited an enhanced growth in high osmotic conditions, such as 1.5 M KCl and 2.5 M D-glucose, com- pared with the vector control cells. In the presence of hydrogen peroxide (H2O2), superoxide anion-generating menadione (MD) and nitric oxide (NO)-generating sodium nitroprusside (SNP), they could grow better than the vector control cells. In the presence of H2O2, MD and SNP and in the absence of a nitrogen source, the S. pombe cells har- boring pYFHos3 contained less elevated NO and reactive oxygen species (ROS) levels than the vector control cells. Collectively, the S. pombe Hos3 also participate in the cel- lular defense against oxidative, nitrosative and nutritional stresses through down-regulating ROS and NO levels." @default.
- W3145932009 created "2021-04-13" @default.
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- W3145932009 date "2015-01-01" @default.
- W3145932009 modified "2023-09-23" @default.
- W3145932009 title "Protective roles of osmotic stress-resistant Hos3 against oxidative, nitrosative and nutritional stresses in Schizosaccharomyces pombe" @default.
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