Matches in SemOpenAlex for { <https://semopenalex.org/work/W3145964306> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W3145964306 endingPage "922" @default.
- W3145964306 startingPage "908" @default.
- W3145964306 abstract "Structural changes in the gut microbial community have been shown to accompany the progressive development of colorectal cancer.In this review we discuss recent hypotheses on the mechanisms involved in the bacteria-mediated carcinogenesis,as well as the triggering factors favoring the shift of the gut microbiota from a mutualistic to a pro-carcinogenic configuration.The possible role of inflammation,bacterial toxins and toxic microbiota metabolites in colorectal cancer onset is specifically discussed.On the other hand,the strategic role of inflammation as the keystone factor in driving microbiota to become carcinogenic is suggested.As a common outcome of different environmental and endogenous triggers,such as diet,aging,pathogen infection or genetic predisposition,inflammation can compromise the microbiota-host mutualism,forcing the increase of pathobionts at the expense of health-promoting groups,and allowing the microbiota to acquire an overall pro-inflammatory configuration.Consolidating inflammation in the gut,and favoring the bloom of toxigenic bacterial drivers,these changes in the gut microbial ecosystem have been suggested as pivotal in promoting carcinogenesis.In this context,it will become of primary importance to implement dietary or probiotics-based interventions aimed at preserving the microbiota-host mutualism along aging,counteracting deviations that favor a pro-carcinogenic microbiota asset." @default.
- W3145964306 created "2021-04-13" @default.
- W3145964306 creator A5004155249 @default.
- W3145964306 creator A5007523303 @default.
- W3145964306 creator A5007974927 @default.
- W3145964306 creator A5015268079 @default.
- W3145964306 creator A5018214080 @default.
- W3145964306 creator A5023638252 @default.
- W3145964306 creator A5036705348 @default.
- W3145964306 creator A5039541029 @default.
- W3145964306 creator A5039633149 @default.
- W3145964306 creator A5044242619 @default.
- W3145964306 creator A5067073986 @default.
- W3145964306 creator A5071130193 @default.
- W3145964306 creator A5073052734 @default.
- W3145964306 date "2014-01-01" @default.
- W3145964306 modified "2023-10-08" @default.
- W3145964306 title "Inflammation and colorectal cancer, when microbiota-host mutualism breaks" @default.
- W3145964306 hasPublicationYear "2014" @default.
- W3145964306 type Work @default.
- W3145964306 sameAs 3145964306 @default.
- W3145964306 citedByCount "0" @default.
- W3145964306 crossrefType "journal-article" @default.
- W3145964306 hasAuthorship W3145964306A5004155249 @default.
- W3145964306 hasAuthorship W3145964306A5007523303 @default.
- W3145964306 hasAuthorship W3145964306A5007974927 @default.
- W3145964306 hasAuthorship W3145964306A5015268079 @default.
- W3145964306 hasAuthorship W3145964306A5018214080 @default.
- W3145964306 hasAuthorship W3145964306A5023638252 @default.
- W3145964306 hasAuthorship W3145964306A5036705348 @default.
- W3145964306 hasAuthorship W3145964306A5039541029 @default.
- W3145964306 hasAuthorship W3145964306A5039633149 @default.
- W3145964306 hasAuthorship W3145964306A5044242619 @default.
- W3145964306 hasAuthorship W3145964306A5067073986 @default.
- W3145964306 hasAuthorship W3145964306A5071130193 @default.
- W3145964306 hasAuthorship W3145964306A5073052734 @default.
- W3145964306 hasConcept C121608353 @default.
- W3145964306 hasConcept C131751744 @default.
- W3145964306 hasConcept C143121216 @default.
- W3145964306 hasConcept C18903297 @default.
- W3145964306 hasConcept C203014093 @default.
- W3145964306 hasConcept C2776914184 @default.
- W3145964306 hasConcept C2777165150 @default.
- W3145964306 hasConcept C526805850 @default.
- W3145964306 hasConcept C539455810 @default.
- W3145964306 hasConcept C54355233 @default.
- W3145964306 hasConcept C555283112 @default.
- W3145964306 hasConcept C86803240 @default.
- W3145964306 hasConceptScore W3145964306C121608353 @default.
- W3145964306 hasConceptScore W3145964306C131751744 @default.
- W3145964306 hasConceptScore W3145964306C143121216 @default.
- W3145964306 hasConceptScore W3145964306C18903297 @default.
- W3145964306 hasConceptScore W3145964306C203014093 @default.
- W3145964306 hasConceptScore W3145964306C2776914184 @default.
- W3145964306 hasConceptScore W3145964306C2777165150 @default.
- W3145964306 hasConceptScore W3145964306C526805850 @default.
- W3145964306 hasConceptScore W3145964306C539455810 @default.
- W3145964306 hasConceptScore W3145964306C54355233 @default.
- W3145964306 hasConceptScore W3145964306C555283112 @default.
- W3145964306 hasConceptScore W3145964306C86803240 @default.
- W3145964306 hasIssue "4" @default.
- W3145964306 hasLocation W31459643061 @default.
- W3145964306 hasOpenAccess W3145964306 @default.
- W3145964306 hasPrimaryLocation W31459643061 @default.
- W3145964306 hasRelatedWork W1973265172 @default.
- W3145964306 hasRelatedWork W2132209276 @default.
- W3145964306 hasRelatedWork W2135648045 @default.
- W3145964306 hasRelatedWork W2338446464 @default.
- W3145964306 hasRelatedWork W2395064609 @default.
- W3145964306 hasRelatedWork W2552930237 @default.
- W3145964306 hasRelatedWork W2746338682 @default.
- W3145964306 hasRelatedWork W2757963838 @default.
- W3145964306 hasRelatedWork W2778803004 @default.
- W3145964306 hasRelatedWork W2787816407 @default.
- W3145964306 hasRelatedWork W2795241760 @default.
- W3145964306 hasRelatedWork W2803660254 @default.
- W3145964306 hasRelatedWork W2891432581 @default.
- W3145964306 hasRelatedWork W2897255284 @default.
- W3145964306 hasRelatedWork W2999424072 @default.
- W3145964306 hasRelatedWork W3030301051 @default.
- W3145964306 hasRelatedWork W3031987056 @default.
- W3145964306 hasRelatedWork W3087179384 @default.
- W3145964306 hasRelatedWork W3201732761 @default.
- W3145964306 hasRelatedWork W3208270617 @default.
- W3145964306 isParatext "false" @default.
- W3145964306 isRetracted "false" @default.
- W3145964306 magId "3145964306" @default.
- W3145964306 workType "article" @default.