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- W3145996980 abstract "Toll like receptors (TLRs) are the cell surface receptors which mainly act by activating innate and adaptive immunity. These TLR’s play very important role in disease resistance through the recognition of pathogen-associated molecular patterns (PAMPs). Among all the TLRs identified <em>TLR2</em> is mainly involved in the recognition of multiple pathogenic microorganisms. In the present study partial region exon-2 of <em>TLR2</em> gene covering 997bp region was characterized in Malnad gidda cattle which is one of the draft breed of cattle which is famous for its disease resistance property. The partial exon-2 of <em>TLR2</em> gene is amplified using self designed primers and subjected for RFLP analysis using <em>BsaA1</em> restriction enzyme which revealed AB genotypes with fragments of sizes 71, 926 and 997bp exhibiting monomorphic pattern. The allelic frequency of A and B allele are 0.5 and the genotypic frequency of the AB genotyope is 1. Further, the observed heterozygositie, polymorphic information content (PIC) and allelic diversity are 1.0, 0.3750 and 0.5 respectively. Sequence analysis of Malnad gidda cattle revealed three SNPs when compared to <em>Bos Taurus</em> sequence." @default.
- W3145996980 created "2021-04-13" @default.
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- W3145996980 date "2021-01-10" @default.
- W3145996980 modified "2023-09-27" @default.
- W3145996980 title "Molecular Characterization and Expression Profile of Partial TLR2 Gene in Malnad Gidda Cattle" @default.
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- W3145996980 doi "https://doi.org/10.20546/ijcmas.2021.1001.334" @default.
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