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- W3146025024 abstract "Objective To investigate the expression of intercellular adhesion molecule 1 (ICAM 1) and vascular adhesion molecule 1 (VCAM 1) in extraocular muscles (EOM) of the eyes with Graves′ opthalmopathy (GO). Methods Seventeen EOM specimens obtained from 16 severe patients with GO and their cryostat sections were observed by double labeling immunohistochemical methods. Results The expression of ICAM 1 was observed in interstitial and perimysial connective tissue surrounding EOM fibers, mononuclear cells, fibroblasts and vascular endothelial cells. Only were vascular endothelial cells stained for VCAM 1, and ICAM 1 and VCAM 1 immunoreactivities were not detected in EOM cells. Conclusions The findings indicate that ICAM 1 and VCAM 1 might be involved in the development of GO, and fibroblasts, vascular endothelial cells and mononuclear cells might play important roles in the autoimmune reaction." @default.
- W3146025024 created "2021-04-13" @default.
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- W3146025024 date "2001-01-01" @default.
- W3146025024 modified "2023-09-25" @default.
- W3146025024 title "A study of adhesion molecule expression in extraocular muscles of Graves′ ophthalmopathy" @default.
- W3146025024 hasPublicationYear "2001" @default.
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