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- W3146029878 abstract "The habitat niches on earth vary considerably in temperature. Accordingly, many biological processes are optimized for different temperatures, the anatomy and physiology of organisms being adapted to their cognate environment. Bacteria are notorious for their ability to colonize different environments. Additionally, the particular niche or lifestyle of many bacteria may be subjected to regular, but sudden, variations in temperature. This reasoning must apply for bacteria adjusting their activities according to seasonal variations, and certainly for pathogens that circulate between the environment, vectors (in some cases) and warm-blooded hosts. Two major problems arise from exposing a cell to a sudden decrease in temperature (Yamanaka et al. 1998). First, membrane fluidity decreases, which affects many vital membrane and membrane-associated functions. Second, nucleic acid topology will be stagnated causing halts in processes such as transcription and translation. In parallel, a bacterium departing its host may need to shut off the expression of colonization functions and, in many instances, the accompanying temperature shift acts as the environmental cue that downregulates virulence gene expression. It follows that bacteria need devices for sensing environmental temperature changes in order to adapt their biochemical processes accordingly. We have attempted to summarize the molecular mechanisms that allow temperature sensing" @default.
- W3146029878 created "2021-04-13" @default.
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- W3146029878 date "2016-01-01" @default.
- W3146029878 modified "2023-09-27" @default.
- W3146029878 title "Low-temperature sensors in bacteria" @default.
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