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- W3146031548 abstract "Children were characterized as having suspected COVID-19 if they were high risk (i e , exposed to a known COVID-19 case) and had at least two of the following features: symptoms (i e , upper respiratory symptoms, digestive symptoms, fever, or fatigue);laboratory abnormalities (i e , normal or decreased white blood cell count, increased lymphocyte count, or increased C-reactive protein);or abnormal chest X-ray Pediatric patients were classified as having confirmed COVID-19 if a nasal, pharyngeal, or blood sample either tested positive for SARS-CoV-2 nucleic acid using real time polymerase chain reaction (RT-PCR) or exhibited highly homologous genetic sequencing with SARS-CoV-2 [ ]each pediatric case was classified by severity: asymptomatic (i e , positive SARS-CoV-2 nucleic test without clinical symptoms or chest imaging abnormalities);mild (i e , symptoms of upper respiratory tract infection or digestive symptoms without auscultory or chest imaging abnormalities);moderate (i e , lung lesions on chest imaging or more severe respiratory symptoms, such as pneumonia without hypoxemia);severe (i e , respiratory symptoms that progress to central cyanosis with oxygen saturation less than 92%);and critical (i e , acute respiratory distress, shock, encephalopathy, myocardial injury, acute kidney injury, or coagulation dysfunction) Specifically, the infant in the case study conducted by Dong and colleagues was positive for both SARS-CoV-2 immunoglobulin G (IgG) and immunoglobulin M (IgM) despite negative SARS-CoV-2 PCR tests 5 Similarly, two of the six neonates studied by H Zeng and colleagues were positive for both SARS-CoV-2 IgG and IgM, and three were positive for IgG 6 Whether a positive SARS-CoV-2 IgM represents a response to infection or is simply a false positive has not been determined yet" @default.
- W3146031548 created "2021-04-13" @default.
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- W3146031548 date "2020-01-01" @default.
- W3146031548 modified "2023-09-27" @default.
- W3146031548 title "COVID-19 and Children" @default.
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