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• W3146032526 abstract "Abstract The application of next generation sequencing (NGS) technology to cytological samples has significantly modified molecular cytopathology practice. Cytological samples represent a valid source of high‐quality DNA for NGS analysis, especially for predicting patients' response to targeted treatments and for refining the risk of malignancy in indeterminate cytological diagnoses. However, several pre‐analytical factors may influence the reliability of NGS clinical analysis. Here, we briefly review the challenges of NGS in cytology practice, focusing on those pre‐analytical factors that may negatively affect NGS success rates and routine diagnostic applications. Finally, we address the future directions of the field." @default.
• W3146032526 created "2021-04-13" @default.
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• W3146032526 date "2021-04-01" @default.
• W3146032526 modified "2023-10-14" @default.
• W3146032526 title "Next generation sequencing in cytology" @default.
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• W3146032526 doi "https://doi.org/10.1111/cyt.12974" @default.
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