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- W3146049500 abstract "We were pleased to see both a case report and accompanying editorial on sugammadex 1, 2. Paton et al. should be congratulated on making several important points related to the use of sugammadex in the ‘cannot ventilate’ scenario. We were interested to note that although the authors predicted difficulty with intubation, they did not predict difficulty with ventilation in their patient, despite a ‘woody neck’ and limited cervical spine movement secondary to radiotherapy. However, they did not mention the degree of jaw or tongue movement, limitations of which are associated with difficult mask ventilation 3, as occurred in the case presented. Despite a previous failed attempt at awake fibreoptic intubation, it is our view that an awake approach was indicated in this case, using either fibreoptic intubation or videolaryngoscopy 4. Paton et al.'s primary approach was the siting of a pre-emptive cricothyroid cannula, followed by intravenous induction of anaesthesia and direct laryngoscopy. However, the authors stated that there was ‘a high likelihood’ of the need for fibreoptic intubation under general anaesthesia, a technique we feel is inadvisable in this case. With upper airway collapse secondary to reduced muscle tone, passage of the fibrescope is likely to be more difficult than when the patient is awake. There was no mention of use of a supraglottic airway device, either to maintain ventilation during fibreoptic intubation in the management plan, to assist failing mask ventilation, or to aid exhalation during attempted transtracheal ventilation. We were similarly surprised that there was no attempt at conventional intubation (either direct or video-assisted): a single attempt under optimal (paralysed) conditions may have led to a secured airway. Finally, the use of sugammadex in this case led to a rapid ‘wake-up’ but with persistent airway obstruction. Even if neuromuscular blockade had been rapid and complete (which may not have been the case at the dosage used), the residual effects of propofol can cause ongoing airway obstruction. There is no assurance that return of spontaneous respiration will lead to satisfactory ventilation and this airway may have remained completely obstructed despite sugammadex reversal, with both jet ventilation via the cricothyroid cannula and a surgical airway more likely to fail after giving sugammadex." @default.
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- W3146049500 date "2013-10-15" @default.
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- W3146049500 title "Sugammadex in anticipated difficult airways4" @default.
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- W3146049500 doi "https://doi.org/10.1111/anae.12466" @default.
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