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- W3146058228 abstract "Genotoxicity of dichlorvos and butachlor on erythrocytes of Rana zhenhaiensis tadpoles was investigated by the alkaline single-cell gel electrophoresis assay or comet assay.Tadpoles were treated for 24h in the laboratory with different concentrations of the testing agents,2.256,4.512,6.768,9.024,11.280mg/L for dichlorvos and 0.292,0.584,0.876,1.168,1.460mg/L for butachlor,to use the comet Assay to test for the significance of dosage responsiveness to an increase in DNA damage,asmeasured by themean DNA tail length-to-width ratio.The concentrations of 4.512mg/L dichlorvos and 0.876mg/L butachlor resulted in highly significant increases in DNA damage of the tadpoles.There were linear correlations between themean DNA tail length-to-width ratio and the concentrations of the two test substances.Our results showed that the two commonly used agricultural chemicals caused dose dependent DNA damage of amphibians,and that comet assaymight be a useful tool formeasuring DNA damage of tadpoles exposed in the field." @default.
- W3146058228 created "2021-04-13" @default.
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- W3146058228 date "2010-12-01" @default.
- W3146058228 modified "2023-10-16" @default.
- W3146058228 title "Genotoxicity of the Pesticide Dichlorvos and Herbicide Butachlor on Rana zhenhaiensis Tadpoles" @default.
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- W3146058228 doi "https://doi.org/10.3724/sp.j.1245.2010.00118" @default.
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