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- W3146059003 abstract "Developmental biology of today is in many ways a different scientific discipline than the one pursued merely a decade ago, not to mention the 'pre.historic' periods of the 1950's.1970's. Nevertheless, many aspects remain more or less unchanged. We are still busy trying to understand fundamental developmental phenomena such as the generation of multicellularity, early embryonic induction and subsequent cell differentiation, and the processes of morphogenesis. Furthermore, we still employ the same vertebrate model systems for these studies, with the exception of the recent appearance of the zebrafish, Daniarerio. So, although the technical advances and the understanding of many molecular interactions enable a more sophisticated design and analysis of experiments, we essentially struggle with the same problems as did our predecessors. The Swedish history of developmental biology includes only a few scientists who worked with the amphibian embryo as their model. In recent years, only two major labs can be identified that have consistently employed amphibians. Some of the accomplishments of S0ren L0vtrup in the field of amphibian embryolo. gy are outlined in more detail in the following paragraphs. Professor L0vtrup has been a very versatile scientist, with interest in fields such as cellular and developmental biology, evolu. tion, biomathematics, and philosophy and history of science. Furthermore, the studies of Professor Jan Lbfberg and his collaborators are worth mentioning. Their work has furthered our understanding of the factors needed for chromatophore development. Using embryos of the urodele Ambystoma mexicanum (the axolotl), they have elegantly shown the importance of com. ponents in the extracellular matrix, both for pigment cell migra. tion and differentiation. Presently, Jan Lbfberg is active in experimental research, whereas very few others in Sweden use the" @default.
- W3146059003 created "2021-04-13" @default.
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- W3146059003 date "1995-01-01" @default.
- W3146059003 modified "2023-09-24" @default.
- W3146059003 title "Swedish contributions to the understanding of amphibian embryogenesis - A phenomenon of the past?" @default.
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