Matches in SemOpenAlex for { <https://semopenalex.org/work/W3146068363> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W3146068363 abstract "Recently, the U.S. Food and Drug Administration (FDA) approved Zohydro®, an extended release formulation of the opioid analgesic hydrocodone that contains no acetaminophen. This approval was against the recommendation of the FDA’s Expert Panel. Subsequently, both chronic pain advocates and anti-drug abuse advocates have steadfastly expressed their support of, or astonishment at this decision. Here, we review the pharmacokinetics, pharmacodynamics, safety and abuse liability of this hydrocodone formulation and how it relates to the Expert Panel’s opinion and the FDA decision. We discuss the important issues, risk mitigation, potential use of abuse deterrents, and how the different viewpoints of the Expert Panel and FDA decision makers resulted in the approval and subsequent controversy." @default.
- W3146068363 created "2021-04-13" @default.
- W3146068363 creator A5045890655 @default.
- W3146068363 date "2014-01-01" @default.
- W3146068363 modified "2023-09-26" @default.
- W3146068363 title "Hydrocodone extended-release: Pharmacodynamics, pharmacokinetics and behavioral pharmacology of a controversy" @default.
- W3146068363 cites W2024012275 @default.
- W3146068363 cites W2337831215 @default.
- W3146068363 hasPublicationYear "2014" @default.
- W3146068363 type Work @default.
- W3146068363 sameAs 3146068363 @default.
- W3146068363 citedByCount "0" @default.
- W3146068363 crossrefType "journal-article" @default.
- W3146068363 hasAuthorship W3146068363A5045890655 @default.
- W3146068363 hasConcept C111113717 @default.
- W3146068363 hasConcept C112705442 @default.
- W3146068363 hasConcept C126322002 @default.
- W3146068363 hasConcept C170493617 @default.
- W3146068363 hasConcept C2776029756 @default.
- W3146068363 hasConcept C2776389719 @default.
- W3146068363 hasConcept C2780035454 @default.
- W3146068363 hasConcept C2781063702 @default.
- W3146068363 hasConcept C3018251022 @default.
- W3146068363 hasConcept C63433958 @default.
- W3146068363 hasConcept C71924100 @default.
- W3146068363 hasConcept C98274493 @default.
- W3146068363 hasConceptScore W3146068363C111113717 @default.
- W3146068363 hasConceptScore W3146068363C112705442 @default.
- W3146068363 hasConceptScore W3146068363C126322002 @default.
- W3146068363 hasConceptScore W3146068363C170493617 @default.
- W3146068363 hasConceptScore W3146068363C2776029756 @default.
- W3146068363 hasConceptScore W3146068363C2776389719 @default.
- W3146068363 hasConceptScore W3146068363C2780035454 @default.
- W3146068363 hasConceptScore W3146068363C2781063702 @default.
- W3146068363 hasConceptScore W3146068363C3018251022 @default.
- W3146068363 hasConceptScore W3146068363C63433958 @default.
- W3146068363 hasConceptScore W3146068363C71924100 @default.
- W3146068363 hasConceptScore W3146068363C98274493 @default.
- W3146068363 hasLocation W31460683631 @default.
- W3146068363 hasOpenAccess W3146068363 @default.
- W3146068363 hasPrimaryLocation W31460683631 @default.
- W3146068363 hasRelatedWork W106834022 @default.
- W3146068363 hasRelatedWork W1212163350 @default.
- W3146068363 hasRelatedWork W1573576543 @default.
- W3146068363 hasRelatedWork W1573843750 @default.
- W3146068363 hasRelatedWork W1591825783 @default.
- W3146068363 hasRelatedWork W2011124934 @default.
- W3146068363 hasRelatedWork W2076492576 @default.
- W3146068363 hasRelatedWork W2088476501 @default.
- W3146068363 hasRelatedWork W2284486963 @default.
- W3146068363 hasRelatedWork W2325410136 @default.
- W3146068363 hasRelatedWork W2413135662 @default.
- W3146068363 hasRelatedWork W2588798634 @default.
- W3146068363 hasRelatedWork W259983218 @default.
- W3146068363 hasRelatedWork W2732794429 @default.
- W3146068363 hasRelatedWork W3048730778 @default.
- W3146068363 hasRelatedWork W3082317079 @default.
- W3146068363 hasRelatedWork W3143671897 @default.
- W3146068363 hasRelatedWork W3185419150 @default.
- W3146068363 hasRelatedWork W577511269 @default.
- W3146068363 hasRelatedWork W2238140263 @default.
- W3146068363 isParatext "false" @default.
- W3146068363 isRetracted "false" @default.
- W3146068363 magId "3146068363" @default.
- W3146068363 workType "article" @default.