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- W3146070270 abstract "肿瘤 suppressor PTEN 包括房间增长，生长，移植，和死亡控制许多生物过程。作为一位主人细胞的管理者， PTEN 本身也受到商讨规定保证它的合适的功能。在 PTEN 规定的缺点在 carcinogenesis 上有深刻影响。在这评论，我们简短有关 PTEN 规定讨论最近的进展并且如此的知识怎么便于我们的理解和 PTEN 的进一步的探索生物学。PTEN 的 carboxyl 尾巴，看起来与 posttranslational 规定的多重类型被联系，将在详细审查下面。进一步，当 p53 需要被激活压制 tumorigenesis (一个休眠看门人) 时， PTEN 和 p53 的比较分析建议， PTEN 可能是对癌症开发的一个组成的监视者，这样一个缺省看门人。" @default.
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- W3146070270 date "2008-01-01" @default.
- W3146070270 modified "2023-09-24" @default.
- W3146070270 title "PTEN： a default gate-keeping tumor suppressor with a versatile tail" @default.
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