Matches in SemOpenAlex for { <https://semopenalex.org/work/W3146074677> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W3146074677 abstract "Nerve growth factor (NGF) can increase expression of dopamine 2 receptors (D2R) in GH3 rat pituitary tumor cells (GH3 cells). As D2R exists in long (D2L) and short (D2S) isoforms, effects of NGF on D2R subtypes have not been accurately evaluated. In this study, we compared mRNA levels of D2R subtypes in GH3 cells treated with or without NGF with real-time RT-PCR. In addition, we also evaluated the relationship between GH3 cell growth after bromocriptine treatment and mRNA lev- els of D2R subtypes. We found that D2R total, D2L, and D2S mRNA in GH3 cells were significantly increased after NGF treatment, compared with the vehicle group. More- over, NGF increased the ratio of D2S to D2L. GH3 cell survival rate after bromocriptine treatment was negatively correlated with D2R total mRNA, and D2S may be more potent than D2L in inhibiting cell growth. Cell apoptosis rate was highly elevated in GH3 cells treated with NGF and bromocriptine, compared with the control group or the group treated with NGF or bromocriptine alone. Our data provide preliminary evidence that the effect of NGF was more prominent on expression of D2S than D2L, in addi- tion, D2S might have a greater impact suppressing GH3 cells growth than D2L." @default.
- W3146074677 created "2021-04-13" @default.
- W3146074677 creator A5026692631 @default.
- W3146074677 creator A5057474948 @default.
- W3146074677 date "2012-01-01" @default.
- W3146074677 modified "2023-09-27" @default.
- W3146074677 title "Differential effects of nerve growth factor on expression of dopamine 2 receptor subtypes in GH3 rat pituitary tumor cells" @default.
- W3146074677 cites W1573258339 @default.
- W3146074677 cites W1891285418 @default.
- W3146074677 cites W1969304986 @default.
- W3146074677 cites W1971802636 @default.
- W3146074677 cites W1974190969 @default.
- W3146074677 cites W1979353921 @default.
- W3146074677 cites W1981781876 @default.
- W3146074677 cites W1991170730 @default.
- W3146074677 cites W2021784043 @default.
- W3146074677 cites W2032832704 @default.
- W3146074677 cites W2050170159 @default.
- W3146074677 cites W2060211196 @default.
- W3146074677 cites W2079388389 @default.
- W3146074677 cites W2087562552 @default.
- W3146074677 cites W2096024465 @default.
- W3146074677 cites W2102541501 @default.
- W3146074677 cites W2112295694 @default.
- W3146074677 cites W2150977935 @default.
- W3146074677 cites W2158287682 @default.
- W3146074677 cites W2168291388 @default.
- W3146074677 hasPublicationYear "2012" @default.
- W3146074677 type Work @default.
- W3146074677 sameAs 3146074677 @default.
- W3146074677 citedByCount "0" @default.
- W3146074677 crossrefType "journal-article" @default.
- W3146074677 hasAuthorship W3146074677A5026692631 @default.
- W3146074677 hasAuthorship W3146074677A5057474948 @default.
- W3146074677 hasConcept C126322002 @default.
- W3146074677 hasConcept C134018914 @default.
- W3146074677 hasConcept C170493617 @default.
- W3146074677 hasConcept C185592680 @default.
- W3146074677 hasConcept C2776856834 @default.
- W3146074677 hasConcept C2778423431 @default.
- W3146074677 hasConcept C2779064019 @default.
- W3146074677 hasConcept C44208683 @default.
- W3146074677 hasConcept C513476851 @default.
- W3146074677 hasConcept C71315377 @default.
- W3146074677 hasConcept C71924100 @default.
- W3146074677 hasConcept C86803240 @default.
- W3146074677 hasConceptScore W3146074677C126322002 @default.
- W3146074677 hasConceptScore W3146074677C134018914 @default.
- W3146074677 hasConceptScore W3146074677C170493617 @default.
- W3146074677 hasConceptScore W3146074677C185592680 @default.
- W3146074677 hasConceptScore W3146074677C2776856834 @default.
- W3146074677 hasConceptScore W3146074677C2778423431 @default.
- W3146074677 hasConceptScore W3146074677C2779064019 @default.
- W3146074677 hasConceptScore W3146074677C44208683 @default.
- W3146074677 hasConceptScore W3146074677C513476851 @default.
- W3146074677 hasConceptScore W3146074677C71315377 @default.
- W3146074677 hasConceptScore W3146074677C71924100 @default.
- W3146074677 hasConceptScore W3146074677C86803240 @default.
- W3146074677 hasLocation W31460746771 @default.
- W3146074677 hasOpenAccess W3146074677 @default.
- W3146074677 hasPrimaryLocation W31460746771 @default.
- W3146074677 hasRelatedWork W1963707420 @default.
- W3146074677 hasRelatedWork W1968118285 @default.
- W3146074677 hasRelatedWork W1993267385 @default.
- W3146074677 hasRelatedWork W1998123216 @default.
- W3146074677 hasRelatedWork W2010084045 @default.
- W3146074677 hasRelatedWork W2012559101 @default.
- W3146074677 hasRelatedWork W2017087950 @default.
- W3146074677 hasRelatedWork W2050456096 @default.
- W3146074677 hasRelatedWork W2062348252 @default.
- W3146074677 hasRelatedWork W2062551812 @default.
- W3146074677 hasRelatedWork W2084509804 @default.
- W3146074677 hasRelatedWork W2093503164 @default.
- W3146074677 hasRelatedWork W2098735718 @default.
- W3146074677 hasRelatedWork W2130985795 @default.
- W3146074677 hasRelatedWork W2138938274 @default.
- W3146074677 hasRelatedWork W2367343670 @default.
- W3146074677 hasRelatedWork W2381160274 @default.
- W3146074677 hasRelatedWork W2391924017 @default.
- W3146074677 hasRelatedWork W2741773173 @default.
- W3146074677 hasRelatedWork W3117308307 @default.
- W3146074677 isParatext "false" @default.
- W3146074677 isRetracted "false" @default.
- W3146074677 magId "3146074677" @default.
- W3146074677 workType "article" @default.