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- W3146075590 abstract "Background In gastric cancer patients who have positive results for peritoneal lavage cytology the disease is defined as CY1, and classified as stage IV, and this population has generally suffered a dismal outcome. For this population, we had conducted a phase II trial, with the 2-year survival rate as the primary endpoint, to test the strategy of D2 dissection followed by chemotherapy with single-agent S-1 (1 M tegafur‐0.4 M gimestat‐1 M otastat potassium). Forty-eight patients were enrolled, of whom 47 were found to have been eligible for analysis. The 2-year survival rate of 46 % exceeded our expectations. Methods Further follow up was conducted to confirm whether radical surgery could be recommended for the CY1 population. Results The 5-year overall and relapse-free survival rates were 26 and 21 %, respectively. Conclusions Gastrectomy with curative intent could be considered for patients with CY1 disease provided they are scheduled to receive effective postoperative chemotherapy." @default.
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- W3146075590 date "2012-01-01" @default.
- W3146075590 modified "2023-09-26" @default.
- W3146075590 title "Long-term follow up of patients who were positive for peritoneal lavage cytology: final report from the CCOG0301 study" @default.
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