FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3146087268> ?p ?o ?g. }

• W3146087268 endingPage "471" @default.
• W3146087268 startingPage "464" @default.
• W3146087268 abstract "Abstract Gestational diabetes mellitus (GDM) is a metabolic dysregulation closely related to both obesity and type 2 diabetes; however, the molecular mechanism underlying GDM is still unclear. The purpose of this study was to investigate the effects of microRNA-377 (miR-377-3p) and fibronectin type III domain containing 5 (FNDC5) in regulating the cell growth of trophoblasts under high glucose (HG) conditions during the development of GDM. Serum miR-377-3p was upregulated and positively correlated with fasting blood glucose level in GDM patients. miR-377-3p downregulation increased the cell vitality and suppressed the cell apoptosis of HG-treated HTR-8/SVneo and BeWo cells. Using TargetScan prediction, luciferase assay, and western blot, it was found that miR-377-3p could target FNDC5 and suppress its expression. However, FNDC5 downregulation abolished the effect of miR-377-3p inhibitor in HTR-8/SVneo cells. Together, miR-377 is a potential target for GDM biomarker, which promotes cell growth and suppresses cell apoptosis, partly through the upregulation of FNDC5." @default.
• W3146087268 created "2021-04-13" @default.
• W3146087268 creator A5011725382 @default.
• W3146087268 creator A5022658778 @default.
• W3146087268 creator A5025657562 @default.
• W3146087268 creator A5055275068 @default.
• W3146087268 creator A5078672073 @default.
• W3146087268 date "2021-01-01" @default.
• W3146087268 modified "2023-09-23" @default.
• W3146087268 title "miR-377 inhibition enhances the survival of trophoblast cells via upregulation of FNDC5 in gestational diabetes mellitus" @default.
• W3146087268 cites W1924912806 @default.
• W3146087268 cites W1976403040 @default.
• W3146087268 cites W2057860524 @default.
• W3146087268 cites W2079577144 @default.
• W3146087268 cites W2085397620 @default.
• W3146087268 cites W2097687832 @default.
• W3146087268 cites W2098365070 @default.
• W3146087268 cites W2151018319 @default.
• W3146087268 cites W2444240676 @default.
• W3146087268 cites W2519631747 @default.
• W3146087268 cites W2595604265 @default.
• W3146087268 cites W2752158340 @default.
• W3146087268 cites W2767603506 @default.
• W3146087268 cites W2790287606 @default.
• W3146087268 cites W2793485880 @default.
• W3146087268 cites W2804400350 @default.
• W3146087268 cites W2946292787 @default.
• W3146087268 cites W2958123991 @default.
• W3146087268 cites W2968777863 @default.
• W3146087268 cites W2982245557 @default.
• W3146087268 cites W2995869873 @default.
• W3146087268 cites W4232215346 @default.
• W3146087268 doi "https://doi.org/10.1515/med-2021-0247" @default.
• W3146087268 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8005781" @default.
• W3146087268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/33817324" @default.
• W3146087268 hasPublicationYear "2021" @default.
• W3146087268 type Work @default.
• W3146087268 sameAs 3146087268 @default.
• W3146087268 citedByCount "3" @default.
• W3146087268 countsByYear W31460872682022 @default.
• W3146087268 countsByYear W31460872682023 @default.
• W3146087268 crossrefType "journal-article" @default.
• W3146087268 hasAuthorship W3146087268A5011725382 @default.
• W3146087268 hasAuthorship W3146087268A5022658778 @default.
• W3146087268 hasAuthorship W3146087268A5025657562 @default.
• W3146087268 hasAuthorship W3146087268A5055275068 @default.
• W3146087268 hasAuthorship W3146087268A5078672073 @default.
• W3146087268 hasBestOaLocation W31460872681 @default.
• W3146087268 hasConcept C104317684 @default.
• W3146087268 hasConcept C126322002 @default.
• W3146087268 hasConcept C127561419 @default.
• W3146087268 hasConcept C134018914 @default.
• W3146087268 hasConcept C145059251 @default.
• W3146087268 hasConcept C1491633281 @default.
• W3146087268 hasConcept C172680121 @default.
• W3146087268 hasConcept C185592680 @default.
• W3146087268 hasConcept C190283241 @default.
• W3146087268 hasConcept C206810289 @default.
• W3146087268 hasConcept C2776415932 @default.
• W3146087268 hasConcept C2776953305 @default.
• W3146087268 hasConcept C2777495146 @default.
• W3146087268 hasConcept C2777605040 @default.
• W3146087268 hasConcept C2779234561 @default.
• W3146087268 hasConcept C2779434492 @default.
• W3146087268 hasConcept C46973012 @default.
• W3146087268 hasConcept C54355233 @default.
• W3146087268 hasConcept C55493867 @default.
• W3146087268 hasConcept C62112901 @default.
• W3146087268 hasConcept C71924100 @default.
• W3146087268 hasConcept C86492073 @default.
• W3146087268 hasConcept C86803240 @default.
• W3146087268 hasConcept C95444343 @default.
• W3146087268 hasConceptScore W3146087268C104317684 @default.
• W3146087268 hasConceptScore W3146087268C126322002 @default.
• W3146087268 hasConceptScore W3146087268C127561419 @default.
• W3146087268 hasConceptScore W3146087268C134018914 @default.
• W3146087268 hasConceptScore W3146087268C145059251 @default.
• W3146087268 hasConceptScore W3146087268C1491633281 @default.
• W3146087268 hasConceptScore W3146087268C172680121 @default.
• W3146087268 hasConceptScore W3146087268C185592680 @default.
• W3146087268 hasConceptScore W3146087268C190283241 @default.
• W3146087268 hasConceptScore W3146087268C206810289 @default.
• W3146087268 hasConceptScore W3146087268C2776415932 @default.
• W3146087268 hasConceptScore W3146087268C2776953305 @default.
• W3146087268 hasConceptScore W3146087268C2777495146 @default.
• W3146087268 hasConceptScore W3146087268C2777605040 @default.
• W3146087268 hasConceptScore W3146087268C2779234561 @default.
• W3146087268 hasConceptScore W3146087268C2779434492 @default.
• W3146087268 hasConceptScore W3146087268C46973012 @default.
• W3146087268 hasConceptScore W3146087268C54355233 @default.
• W3146087268 hasConceptScore W3146087268C55493867 @default.
• W3146087268 hasConceptScore W3146087268C62112901 @default.
• W3146087268 hasConceptScore W3146087268C71924100 @default.
• W3146087268 hasConceptScore W3146087268C86492073 @default.
• W3146087268 hasConceptScore W3146087268C86803240 @default.
• W3146087268 hasConceptScore W3146087268C95444343 @default.
• W3146087268 hasIssue "1" @default.
• W3146087268 hasLocation W31460872681 @default.

• next