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- W3146102270 abstract "We investigated the prevalence of neutralizing antibodies (NA) to human Adenovirus (Ad) 5 both in healthy subjects (HS) and Chronic Hepatitis B (CHB) patients in Shanghai. Detection of anti-Ad5 NA (percent- age of detection and titers) was similar between HS and CHB patients. A high percentage of subjects harbored no detectable antibodies (32.2 %) while proportion of subjects displaying very high antibody titers was low (4 %). Neither demographic factors (gender, age, health) nor AST/ALT or HBV circulating DNA titers affected detection of Ad5- specific NA. These observations pave the ground for development of Ad5-based immunotherapeutics aiming at treating CHB patients in China." @default.
- W3146102270 created "2021-04-13" @default.
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- W3146102270 date "2015-01-01" @default.
- W3146102270 modified "2023-09-27" @default.
- W3146102270 title "The sero-prevalence of anti-adenovirus 5 neutralizing antibodies is independent of a chronic hepatitis B carrier state in China" @default.
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