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- W3146353345 abstract "Genetic evidence suggests a role for the Wnt/β-catenin pathway in gastric cancer. However, Wnt5a, regarded as a prototypical non-canonical Wnt ligand, has also been extensively associated with this disease. Therefore, the roles of the Wnt signaling pathway in gastric cancer initiation and progression, and particularly the precise mechanisms by which the non-canonical Wnt pathway might promote the development and progression of gastric cancer, are not entirely well understood. This article analyzes publicly available gene and protein expression data and reveals the existence of a WNT5A / FZD2 / FZD7 / ROR2 signature, which correlates with tumor-infiltrating and mesenchymal cell marker expression. High expression of FZD7 and ROR2 correlates with a shared gene and protein expression profile, which in turn correlates with poor prognosis. In summary, the findings presented in this article provide an updated view of the relative contributions of the Wnt/β-catenin and non-canonical Wnt pathways in gastric cancer." @default.
- W3146353345 created "2021-04-13" @default.
- W3146353345 creator A5032426471 @default.
- W3146353345 date "2021-04-01" @default.
- W3146353345 modified "2023-10-17" @default.
- W3146353345 title "A Non-canonical Wnt Signature Correlates With Lower Survival in Gastric Cancer" @default.
- W3146353345 cites W1971085650 @default.
- W3146353345 cites W1979085392 @default.
- W3146353345 cites W1979340580 @default.
- W3146353345 cites W1989662404 @default.
- W3146353345 cites W1989874581 @default.
- W3146353345 cites W1991528151 @default.
- W3146353345 cites W1996130952 @default.
- W3146353345 cites W1999086631 @default.
- W3146353345 cites W2001670860 @default.
- W3146353345 cites W2003380289 @default.
- W3146353345 cites W2007381839 @default.
- W3146353345 cites W2009684443 @default.
- W3146353345 cites W2013891209 @default.
- W3146353345 cites W2031153174 @default.
- W3146353345 cites W2031279966 @default.
- W3146353345 cites W2032810718 @default.
- W3146353345 cites W2035523809 @default.
- W3146353345 cites W2049397238 @default.
- W3146353345 cites W2049491375 @default.
- W3146353345 cites W2050783606 @default.
- W3146353345 cites W2064153835 @default.
- W3146353345 cites W2066088895 @default.
- W3146353345 cites W2070388817 @default.
- W3146353345 cites W2071904977 @default.
- W3146353345 cites W2082574041 @default.
- W3146353345 cites W2087667264 @default.
- W3146353345 cites W2094018565 @default.
- W3146353345 cites W2099011309 @default.
- W3146353345 cites W2104866423 @default.
- W3146353345 cites W2112173990 @default.
- W3146353345 cites W2112781335 @default.
- W3146353345 cites W2114843025 @default.
- W3146353345 cites W2119284420 @default.
- W3146353345 cites W2126547130 @default.
- W3146353345 cites W2140328069 @default.
- W3146353345 cites W2144796426 @default.
- W3146353345 cites W2147257521 @default.
- W3146353345 cites W2149441684 @default.
- W3146353345 cites W2153646243 @default.
- W3146353345 cites W2154041910 @default.
- W3146353345 cites W2155002380 @default.
- W3146353345 cites W2155348369 @default.
- W3146353345 cites W2158673376 @default.
- W3146353345 cites W2171620774 @default.
- W3146353345 cites W2290454971 @default.
- W3146353345 cites W2411765633 @default.
- W3146353345 cites W2463600666 @default.
- W3146353345 cites W2581016917 @default.
- W3146353345 cites W2607129810 @default.
- W3146353345 cites W2622027041 @default.
- W3146353345 cites W2731935184 @default.
- W3146353345 cites W2737138474 @default.
- W3146353345 cites W2765224588 @default.
- W3146353345 cites W2765974598 @default.
- W3146353345 cites W2789397544 @default.
- W3146353345 cites W2792699897 @default.
- W3146353345 cites W2810069507 @default.
- W3146353345 cites W2811106767 @default.
- W3146353345 cites W2889646458 @default.
- W3146353345 cites W2890790155 @default.
- W3146353345 cites W2900569176 @default.
- W3146353345 cites W2901068426 @default.
- W3146353345 cites W2908622178 @default.
- W3146353345 cites W2928665623 @default.
- W3146353345 cites W2936641871 @default.
- W3146353345 cites W2946173685 @default.
- W3146353345 cites W2946657092 @default.
- W3146353345 cites W2948949781 @default.
- W3146353345 cites W2974998460 @default.
- W3146353345 cites W2992471949 @default.
- W3146353345 cites W3000030945 @default.
- W3146353345 cites W3010566911 @default.
- W3146353345 cites W3011232347 @default.
- W3146353345 cites W3020814180 @default.
- W3146353345 cites W3029182650 @default.
- W3146353345 cites W3033202797 @default.
- W3146353345 cites W3039457224 @default.
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- W3146353345 doi "https://doi.org/10.3389/fcell.2021.633675" @default.
- W3146353345 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8047116" @default.
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