Matches in SemOpenAlex for { <https://semopenalex.org/work/W3146461161> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W3146461161 abstract "There is increasing evidence of an association between attention deficit/hyperactivity disorder (ADHD) and depression, but potential mechanisms explaining this are unclear. The overall aim of this thesis was to expand the current literature by investigating different factors that might contribute to the association between ADHD and depression, and to examine the impact of ADHD on the clinical presentation of depression.First, the prospective association between childhood ADHD and adolescent depression was investigated and academic attainment and friendship difficulties were tested as mediators of this association. In a general population sample, ADHD at age 7 was associated with depression 10 years later. Part of this association was mediated by academic attainment and friendship difficulties.Second, friendships were examined in more detail by testing different features of friendship (presence of friends, quality of friendships and the characteristics of thefriendship group) as mediators of the association between ADHD and depression. In addition, I tested whether parent-child relationship quality could mitigate against friendship difficulties. In a sample of secondary school pupils, friendship quality mediated part of the association between ADHD and depression 7 months later, and mother-child relationship warmth appeared to slightly mitigate against this mediation effect.Third, the genetic overlap of ADHD and major depressive disorder (MDD) was examined by identifying specific regions of the genome that might contribute to the genetic overlap. In a genome-wide association (GWA) study meta-analysis of ADHD and MDD, 14 shared genomic regions were identified, nine of which were not highlighted previously in individual ADHD or MDD GWA studies.Finally, the impact of ADHD on depression clinical presentation was investigated. In a prospective cohort of recurrently depressed adults, ADHD was associated withfeatures of depression presentation, including an earlier age at onset and greater impairment, recurrence, odds of self-harm or suicide attempt and taking nonstandard depression medication." @default.
- W3146461161 created "2021-04-13" @default.
- W3146461161 creator A5084572493 @default.
- W3146461161 date "2020-01-01" @default.
- W3146461161 modified "2023-09-27" @default.
- W3146461161 title "Investigating the link between attention deficit/hyperactivitydisorder and depression" @default.
- W3146461161 hasPublicationYear "2020" @default.
- W3146461161 type Work @default.
- W3146461161 sameAs 3146461161 @default.
- W3146461161 citedByCount "0" @default.
- W3146461161 crossrefType "dissertation" @default.
- W3146461161 hasAuthorship W3146461161A5084572493 @default.
- W3146461161 hasConcept C118552586 @default.
- W3146461161 hasConcept C138496976 @default.
- W3146461161 hasConcept C139719470 @default.
- W3146461161 hasConcept C142853389 @default.
- W3146461161 hasConcept C15744967 @default.
- W3146461161 hasConcept C162324750 @default.
- W3146461161 hasConcept C17744445 @default.
- W3146461161 hasConcept C179420905 @default.
- W3146461161 hasConcept C199539241 @default.
- W3146461161 hasConcept C2776867660 @default.
- W3146461161 hasConcept C2778736484 @default.
- W3146461161 hasConcept C2779297142 @default.
- W3146461161 hasConcept C2780051608 @default.
- W3146461161 hasConcept C2780733359 @default.
- W3146461161 hasConcept C2780783007 @default.
- W3146461161 hasConcept C2908647359 @default.
- W3146461161 hasConcept C50522688 @default.
- W3146461161 hasConcept C542102704 @default.
- W3146461161 hasConcept C70410870 @default.
- W3146461161 hasConcept C71924100 @default.
- W3146461161 hasConcept C77805123 @default.
- W3146461161 hasConcept C99454951 @default.
- W3146461161 hasConceptScore W3146461161C118552586 @default.
- W3146461161 hasConceptScore W3146461161C138496976 @default.
- W3146461161 hasConceptScore W3146461161C139719470 @default.
- W3146461161 hasConceptScore W3146461161C142853389 @default.
- W3146461161 hasConceptScore W3146461161C15744967 @default.
- W3146461161 hasConceptScore W3146461161C162324750 @default.
- W3146461161 hasConceptScore W3146461161C17744445 @default.
- W3146461161 hasConceptScore W3146461161C179420905 @default.
- W3146461161 hasConceptScore W3146461161C199539241 @default.
- W3146461161 hasConceptScore W3146461161C2776867660 @default.
- W3146461161 hasConceptScore W3146461161C2778736484 @default.
- W3146461161 hasConceptScore W3146461161C2779297142 @default.
- W3146461161 hasConceptScore W3146461161C2780051608 @default.
- W3146461161 hasConceptScore W3146461161C2780733359 @default.
- W3146461161 hasConceptScore W3146461161C2780783007 @default.
- W3146461161 hasConceptScore W3146461161C2908647359 @default.
- W3146461161 hasConceptScore W3146461161C50522688 @default.
- W3146461161 hasConceptScore W3146461161C542102704 @default.
- W3146461161 hasConceptScore W3146461161C70410870 @default.
- W3146461161 hasConceptScore W3146461161C71924100 @default.
- W3146461161 hasConceptScore W3146461161C77805123 @default.
- W3146461161 hasConceptScore W3146461161C99454951 @default.
- W3146461161 hasLocation W31464611611 @default.
- W3146461161 hasOpenAccess W3146461161 @default.
- W3146461161 hasPrimaryLocation W31464611611 @default.
- W3146461161 hasRelatedWork W1964542373 @default.
- W3146461161 hasRelatedWork W1980845142 @default.
- W3146461161 hasRelatedWork W1988615509 @default.
- W3146461161 hasRelatedWork W1997801859 @default.
- W3146461161 hasRelatedWork W2000675634 @default.
- W3146461161 hasRelatedWork W2048306059 @default.
- W3146461161 hasRelatedWork W2065927983 @default.
- W3146461161 hasRelatedWork W2076269631 @default.
- W3146461161 hasRelatedWork W2098478156 @default.
- W3146461161 hasRelatedWork W2134636507 @default.
- W3146461161 hasRelatedWork W2208490857 @default.
- W3146461161 hasRelatedWork W2888942827 @default.
- W3146461161 hasRelatedWork W2890348363 @default.
- W3146461161 hasRelatedWork W2979907696 @default.
- W3146461161 hasRelatedWork W2999035753 @default.
- W3146461161 hasRelatedWork W3039062806 @default.
- W3146461161 hasRelatedWork W3183331993 @default.
- W3146461161 hasRelatedWork W3184873528 @default.
- W3146461161 hasRelatedWork W3185451244 @default.
- W3146461161 hasRelatedWork W3209706732 @default.
- W3146461161 isParatext "false" @default.
- W3146461161 isRetracted "false" @default.
- W3146461161 magId "3146461161" @default.
- W3146461161 workType "dissertation" @default.